SART3

Gene Symbol SART3
Entrez Gene 9733
Alt Symbol DSAP1, P100, RP11-13G14, TIP110, p110, p110(nrb)
Species Human
Gene Type protein-coding
Description squamous cell carcinoma antigen recognized by T cells 3
Other Description SART-3|hSART-3|p110 nuclear RNA-binding protein|squamous cell carcinoma antigen recognized by T-cells 3|tat-interacting protein of 110 kDa
Swissprots Q2M2H0 A8K2E4 Q96J95 Q8IUS1 Q15020 Q58F06 B7ZKM0
Accessions EAW97816 EAW97817 Q15020 AB020880 BAA78384 AB073647 AF387506 AAK69347 AI656011 AK225174 AK290209 BAF82898 AK299250 BAG61281 AK302332 BAG63664 AK304834 BAG65578 BC004547 BC015627 BC024279 BC032601 AAH32601 BC041638 AAH41638 BC093784 AAH93784 BC103706 AAI03707 BC111983 AAI11984 BC143253 AAI43254 BQ231651 CN349201 CR933631 D63879 BAA09929 DA391623 XM_005269241 XP_005269298 XM_011539026 XP_011537328 NM_014706 NP_055521
Function U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation (PubMed:12032085). Also binds U6atac snRNPs and may function as a recycling factor for U4atac/U6atac spliceosomal snRNP, an initial step in the assembly of U12-type spliceosomal complex. The U12-type spliceosomal complex plays a role in the splicing of introns with non-canonical splice sites (PubMed:14749385). May also function as a substrate-targeting factor for deubiquitinases like USP4 and USP15. Recruits USP4 to ubiquitinated PRPF3 within the U4/U5/U6 tri-snRNP complex, promoting PRPF3 deubiquitination and thereby regulating the spliceosome U4/U5/U6 tri-snRNP spliceosomal complex disassembly (PubMed:20595234). May also recruit the deubiquitinase USP15 to histone H2B and mediate histone deubiquitination, thereby regulating gene expression and/or DNA repair (PubMed:24526689). Ma
Subcellular Location Nucleus, nucleoplasm {ECO:0000269|PubMed:10463607, ECO:0000269|PubMed:11959860, ECO:0000269|PubMed:12578909}. Nucleus, Cajal body {ECO:0000269|PubMed:12578909}. Nucleus speckle {ECO:0000269|PubMed:11959860}. Cytoplasm {ECO:0000269|PubMed:10463607, ECO:0000269|PubMed:11959860}.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:11959860}.

SART-3 (N-17) - sc-244068 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SART-3 (N-17): sc-244068. Western blot analysis of SART-3 expression in K-562 whole cell lysate.

Anti-SART3 antibody - ab176822 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SART3 antibody (ab176822) at 0.02 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgdeveloped using the ECL technique

Anti-SART3 antibody - ab169302 from Abcam

Host Mouse
Clonality Polyclonal
Anti-SART3 antibody (ab169302) at 1/500 dilution + Human pancreas lysate at 50 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilutiondeveloped using the ECL technique

Anti-SART3 antibody - ab36137 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-SART3 antibody (ab36137) at 1 µg/ml + Daudi lysate (RIPA buffer, 30µg total protein per lane).

Anti-SART3 antibody - ab84671 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab84671 at 1/100 dilution, staining SART3 in Formalin-Fixed Paraffin-Embedded Human pancreatic islet cell tumor tissue by Immunofluorescence. Detection: Redfluorescent goat anti-rabbit IgG highly cross-adsorbed Antibody at a dilution of 1/100.

Anti-SART3 antibody - ab90871 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-SART3 antibody (ab90871) at 1 µg/ml + Human fetal small intestine lysate at 10 µgSecondaryanti-Rabbit IgG HRP at 1/50000 dilution

Anti-SART3 antibody - C-terminal - ab155765 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SART3 antibody - C-terminal (ab155765) at 1/1000 dilutionLane 1 : A431 whole cell lysateLane 2 : H1299 whole cell lysateLane 3 : HeLa whole cell lysateLane 4 : HepG2 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-SART3 Antibody (aa951-963) - LS-C55436 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody staining (0.01 ug/ml) of Jurkat cell lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.

Anti-SART3 Antibody (N-Terminus) - LS-C31583 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
SART3 antibody LS-C31583 was used in IHC to stain formalin-fixed, paraffin-embedded human liver.

Anti-SART3 Antibody (C-Terminus) - LS-C107940 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SART3 antibody LS-C107940 Western blot of HT1080 cell lysate.

Anti-SART3 Antibody (aa913-963) - LS-C288315 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SART3 Antibody (aa827-876) - LS-C109897 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SART3 antibody LS-C109897 Western blot of Fetal Small Intestine lysate.

Anti-SART3 Antibody - LS-C334411 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using SART3 antibody.

Anti-SART3 Antibody (aa600-650) - LS-C288313 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human SART3/TIP110 by Immunohistochemistry and Immunofluorescence. Sample: FFPE sections of human ovarian carcinoma (left) and colon carcinoma (right). Antibody: Affinity purified rabbit anti-SART3/TIP110 used at a dilution of 1:200 (1 ug/ml) and 1:400 (0.5 ug/ml). Detection: DAB and Red-fluorescent Goat anti-Rabbit IgG-heavy and light chain, cross-adsorbed Antibody DyLight 594 Conjugated used at a dilution of 1:100.

Anti-SART3 Antibody (aa600-650) - LS-C286534 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human SART3/TIP110 by Immunohistochemistry. Sample: FFPE section of human pancreatic islet cell tumor. Antibody: Affinity purified rabbit anti-SART3/TIP110 used at a dilution of 1:250.

SART3 Antibody - NB100-74648 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SART3 Antibody [NB100-74648] - Detection of Human SART3/TIP110 on HeLa whole cell lysate using NB100-74648. SART3 was also immunoprecipitated by rabbit anti-SART3 antibody NB100-74649.

SART3 Antibody - NBP2-13281 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: SART3 Antibody [NBP2-13281] - Staining of human cerebellum shows strong nuclear positivity in Purkinje cells.

SART3 Antibody - NBP1-31487 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SART3 Antibody - H00009733-B01 from Novus Biologicals

Host Mouse
Clonality Polyclonal
Western Blot: SART3 Antibody [H00009733-B01] - SART3 MaxPab polyclonal antibody (B01), Lot # 08058 WULz. Western Blot analysis of SART3 expression in human pancreas.

SART3 Antibody (2G2) - NB120-10435 from Novus Biologicals

Prices $279.00
Sizes 25 µg
Host Mouse
Clonality Monoclonal
Clone 2G2

SART3 Antibody - NB100-1893 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: SART3 Antibody [NB100-1893] - (1ug/ml) analysis of Daudi lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

SART3 Antibody (2G2) [Allophycocyanin] - NB120-10435APC from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone 2G2

SART3 Antibody (2G2) [DyLight 350] - NB120-10435UV from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone 2G2

SART3 Antibody (2G2) [DyLight 488] - NB120-10435G from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone 2G2

SART3 Antibody (2G2) [DyLight 405] - NB120-10435V from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone 2G2
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