CYP8B1

Gene Symbol	CYP8B1
Entrez Gene	1582
Alt Symbol	CP8B, CYP12
Species	Human
Gene Type	protein-coding
Description	cytochrome P450, family 8, subfamily B, polypeptide 1
Other Description	7 alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase|7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase|7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase|CYPVIIIB1|cytochrome P450 8B1|cytochrome P450, subfamily VIIIB (sterol 12-alpha-hydroxylase), polypeptide 1|sterol 12-alpha-hydroxylase
Swissprots	O75958 Q6NWT3 Q9UNU6 Q6NWT2 B2RCY3
Accessions	AAD19877 EAW64682 Q9UNU6 AF090318 AAC63037 AK310784 AK315330 BAG37730 BC067434 AAH67434 BC067441 AAH67441 BC067442 AAH67442 BC067443 BC067444 AAH67444 NM_004391 NP_004382
Function	Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha- hydroxylated C27 steroids.
Subcellular Location	Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.
Tissue Specificity	Liver.
Top Pathways	Primary bile acid biosynthesis, PPAR signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CYP8B1 Antibody Blocking Peptide - LS-E22022 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CYP8B1 Antibody Blocking Peptide - LS-E9780 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CYP8B1-Antibody-C-term-Blocking-Peptide - BP8787b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CYP8B1-Antibody-N-term-Blocking-Peptide - BP8787a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CYP8B1 Blocking Peptide - 33R-8610 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Cytochrome P450 8B1 Blocking Peptide - abx062518 from Abbexa Category Peptide Species Human, Mouse, Rat

Cytochrome P450 8B1 Blocking Peptide - abx064145 from Abbexa Category Peptide Species Human, Mouse, Rat

Cytochrome P450 8B1 Blocking Peptide - CBP1324 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

Cytochrome P450 8B1 Blocking Peptide - CBP2951 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

CYP8B1 Peptide - BS5986P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase(CYP8B1) - CSB-YP890945HU CSB-EP890945HU CSB-BP890945HU CSB-MP890945HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CYP8B1 Peptide, Human - M34GP03990H from Creative Peptides Category Peptide Source Synthetic. Species Human

CYP8B1 peptide - orb218814 from Biorbyt Category Peptide Species Human, Mouse, Rat

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