GLI1

Gene Symbol	GLI1
Entrez Gene	2735
Alt Symbol	GLI
Species	Human
Gene Type	protein-coding
Description	GLI family zinc finger 1
Other Description	GLI-Kruppel family member GLI1|glioma-associated oncogene 1|glioma-associated oncogene homolog 1 (zinc finger protein)|oncogene GLI|zinc finger protein GLI1
Swissprots	F5H6H8 D0EUY3 Q8TDN9 E9PQQ9 P08151
Accessions	AAM13391 BAN82437 EAW97013 P08151 AB239135 BAG16751 AB239136 AB239328 AB558490 BAN82438 AK297899 BAG60219 BC013000 AAH13000 GQ890670 ACX35434 X07384 CAA30297 XM_005268799 XP_005268856 XM_011538189 XP_011536491 XM_011538190 XP_011536492 NM_001160045 NP_001153517 NM_001167609 NP_001161081 NM_005269 NP_005260
Function	Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation. {ECO:0000269|PubMed:10806483, ECO:0000269|PubMed:11238441}.
Subcellular Location	Cytoplasm. Nucleus. Note=Tethered in the cytoplasm by binding to SUFU. Activation and translocation to the nucleus is promoted by interaction with STK36. Phosphorylation by ULK3 may promote nuclear localization. Translocation to the nucleus is promoted by interaction with ZIC1.
Tissue Specificity	Testis, myometrium and fallopian tube. Also expressed in the brain with highest expression in the cerebellum, optic nerve and olfactory tract. {ECO:0000269|PubMed:19878745}.
Top Pathways	Hedgehog signaling pathway, Basal cell carcinoma, cAMP signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Gli1 peptide - ab86150 from Abcam Category Peptide Species Human

Human Gli1 peptide - ab111659 from Abcam Category Peptide Species Human

Human Gli1 protein fragment - ab152427 from Abcam Category Protein Source Wheat germ Species Human

Human Gli1 protein fragment - ab152428 from Abcam Category Protein Source Wheat germ Species Human

Mouse Gli1 peptide - ab201523 from Abcam Category Peptide Species Mouse

Recombinant Human GLI-1 Protein - H00002735-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Gli1 blocking peptide - GTX88600-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Human GLI1 1 protein - orb245543 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

GLI1 - H00002735-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

GLI1 - H00002735-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

GLI1 - H00002735-Q02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

GLI1 - H00002735-Q02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

GLI1 Control Peptide - AP05303CP-N from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

GLI1 fusion protein - ag15081 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

GLI1 fusion protein - Ag22962 from Proteintech Group Category Protein Prices $199.00 Sizes 50 Source E. coli -derived, PGEX-4T Species Human

Recombinant GLI Family Zinc Finger Protein 1 (GLI1) - RPJ729Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant GLI Family Zinc Finger Protein 1 (GLI1) - RPJ729Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant human Zinc finger protein GLI1 - CSB-EP129894h CSB-BP129894h CSB-MP129894h from Cusabio Category Protein Source E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Zinc finger protein GLI1(GLI1),partial - CSB-RP129894h from Cusabio Category Protein Source E.coli Species Human

Recombinant Human Zinc finger protein GLI1(GLI1) ,partial - CSB-YP009499HU CSB-EP009499HU CSB-BP009499HU CSB-MP009499HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

GLI1 Peptide (OEEG01190) - OEEG01190 from Aviva Systems Biology Category Peptide Prices $150.00 Sizes 50 µg Source Rabbit Species Human

GLI1 Protein - abx164523 from Abbexa Category Protein Species Human, Mouse, Rat

GLI1 - TP301110 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Zinc finger protein GLI1(GLI1) ,partial, Recombinant Protein - MBS957438 from MyBioSource Category Protein Prices $180.00, $490.00, $715.00, $950.00, $1,055.00, $1,170.00, $1,170.00, $1,390.00, $1,620.00, $1,850.00 Sizes 50 µg (E-Coli), 200 µg (E-Coli), 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 1 mg (E-Coli), 50 µg (Mammalian-Cell), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Zinc Finger Protein GLI1, Peptide - MBS396385 from MyBioSource Category Protein Prices $195.00 Sizes 50 µg Source Rabbit Species Human

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