GLI1

Gene Symbol GLI1
Entrez Gene 2735
Alt Symbol GLI
Species Human
Gene Type protein-coding
Description GLI family zinc finger 1
Other Description GLI-Kruppel family member GLI1|glioma-associated oncogene 1|glioma-associated oncogene homolog 1 (zinc finger protein)|oncogene GLI|zinc finger protein GLI1
Swissprots F5H6H8 D0EUY3 Q8TDN9 E9PQQ9 P08151
Accessions AAM13391 BAN82437 EAW97013 P08151 AB239135 BAG16751 AB239136 AB239328 AB558490 BAN82438 AK297899 BAG60219 BC013000 AAH13000 GQ890670 ACX35434 X07384 CAA30297 XM_005268799 XP_005268856 XM_011538189 XP_011536491 XM_011538190 XP_011536492 NM_001160045 NP_001153517 NM_001167609 NP_001161081 NM_005269 NP_005260
Function Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation. {ECO:0000269|PubMed:10806483, ECO:0000269|PubMed:11238441}.
Subcellular Location Cytoplasm. Nucleus. Note=Tethered in the cytoplasm by binding to SUFU. Activation and translocation to the nucleus is promoted by interaction with STK36. Phosphorylation by ULK3 may promote nuclear localization. Translocation to the nucleus is promoted by interaction with ZIC1.
Tissue Specificity Testis, myometrium and fallopian tube. Also expressed in the brain with highest expression in the cerebellum, optic nerve and olfactory tract. {ECO:0000269|PubMed:19878745}.
Top Pathways Hedgehog signaling pathway, Basal cell carcinoma, cAMP signaling pathway

GLI1 Antibody - 2553 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of total cell lysates from A549 and RMS-13 cells using GLI1 Antibody.

GLI1 (C68H3) Rabbit mAb - 3538 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone C68H3
Western blot analysis of extracts from RMS-13 and TOV-112D cells using GLI1 (C68H3) Rabbit mAb.

GLI1 (L42B10) Mouse mAb - 2643 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Mouse
Clonality Monoclonal
Clone L42B10
Western blot analysis of extracts from RMS-13 and TOV-112D cells using GLI1 (L42B10) Mouse mAb.

GLI1 (V812) Antibody - 2534 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from RMS-13 and TOV-112D cells using GLI1 (V812) Antibody.

GLI-1 (H-300) - sc-20687 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
GLI-1 (H-300): sc-20687. Immunoperoxidase staining of formalin fixed, paraffin-embedded human testis tissue showing nuclear staining of ductus seminiferus cells and cytoplasmic staining of Leydig cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

GLI-1 (C-18) - sc-6152 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

GLI-1 (N-16) - sc-6153 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GLI-1 (N-16): sc-6153. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

Anti-Gli1 antibody - ab167388 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Gli1 antibody (ab167388) at 1 µg/mlLane 1 : E14 Mouse Embryo Brain Tissue LysateLane 2 : E16 Ms Embryo Brain Tissue LysateLane 3 : E18 Ms Embryo Brain Tissue LysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/50000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Gli1 antibody - ab94927 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Gli1 antibody (ab94927) at 10 µg/ml + RMS-13 lysate at 15 µgSecondaryMouse anti-rabbit HRP at 1/200000 dilution

Anti-Gli1 antibody [EPR4523] - ab134906 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4523
Anti-Gli1 antibody [EPR4523] (ab134906) at 1/1000 dilution (purified) + RMS13 cell lysate at 10 µgSecondaryHRP goat anti-rabbit (H+L) at 1/1000 dilution

Anti-Gli1 antibody - N-terminal - ab187320 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Gli1 antibody - N-terminal (ab187320) at 1/1000 dilution + Mouse brain total cell extract

Anti-GLI / GLI1 Antibody (aa755-1106, clone 4E2) - LS-C338944 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4E2
IHC of paraffin-embedded Human muscle tissue using anti-GLI1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

Anti-GLI / GLI1 Antibody (aa768-1106) - LS-C343972 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Gli1 antibody IHC-paraffin: Human Intestinal Cancer Tissue.

Anti-GLI / GLI1 Antibody (aa1-237) - LS-C36436 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-GLI / GLI1 Antibody (Gly420) - LS-C36437 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GLI / GLI1 Antibody - LS-C66527 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-GLI / GLI1 Antibody (aa1-234) - LS-C66528 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rat
Clonality Monoclonal

Anti-GLI / GLI1 Antibody (N-Terminus) - LS-C31476 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
A: Marker, B: Jurkat Cell Lysate

Anti-GLI / GLI1 Antibody (aa1007-1056) - LS-C31477 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
A: Marker, B: HepG2 Cell Lysate

Anti-GLI / GLI1 Antibody - LS-C150725 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GLI / GLI1 Antibody (Biotin) - LS-C180590 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GLI / GLI1 Antibody - LS-C140618 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of GLI1 antibody (LS-C140618) on RMS-13 lysate. Lysate used at 15 ug/lane. Antibody used at 10 ug/ml. Secondary antibody, mouse anti-rabbit HRP, used at 1:200k dilution.

Anti-GLI / GLI1 Antibody (DY650) - LS-C180591 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GLI / GLI1 Antibody (DY488) - LS-C180592 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GLI / GLI1 Antibody - LS-C140617 from LifeSpan Bioscience

Prices $460.00
Sizes 10 blot
Host Rabbit
Clonality Polyclonal
Western blot of GLI1 antibody (LS-C140617) on RMS-13 cell lysate. Lysate used at 15 ug/lane. Antibody used at 1:200 (lane 1) and 1:400 (lane 2) dilution. Secondary antibody, mouse anti-rabbit HRP, used at 1:75k dilution.
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