SNX17

Gene Symbol SNX17
Entrez Gene 9784
Alt Symbol -
Species Human
Gene Type protein-coding
Description sorting nexin 17
Other Description sorting nexin-17
Swissprots Q53HN7 Q6IAS3 B4DQM7 Q15036
Accessions AAY14844 CAC12897 CAH05526 EAX00584 EAX00585 EAX00586 Q15036 AK129689 AK222543 BAD96263 AK293252 BAG56784 AK293464 BAG56959 AK295278 BAG58262 AK297054 BAG59579 AK298620 BAG60799 AK298856 BAG60979 AK298869 BAG60989 AK300144 BAG61930 AK300641 BAG62330 AK307122 AK308487 AK309640 AK316373 BAH14744 BC002524 AAH02524 BC002610 AAH02610 BC014620 AAH14620 BC021108 BC032320 BC050590 AAH50590 BT007167 AAP35831 CR457081 CAG33362 D31764 BAA06542 DB177194 XM_011533203 XP_011531505 NM_001267059 NP_001253988 NM_001267060 NP_001253989 NM_001267061 NP_001253990 NM_014748 NP_055563 NR_049782 NR_049783 NR_049784 NR_049785 NR_049786 NR_049787 NR_049788
Function Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)). {ECO:0000269|PubMed:15121882, ECO:0000269|PubMed:15769472, ECO:0000269|PubMed:16712798, ECO:0000269|PubMed:19005208, ECO:0000269|PubMed:21512128, ECO:0000269|PubMed:22492727}.
Subcellular Location Cytoplasm. Early endosome. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.

SNX17-Over-expression-Lysate - LY14331a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag SNX17 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SNX17 gene.

SNX17 293T Cell Transient Overexpression Lysate(Denatured) - H00009784-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

SNX17 overexpression lysate - LY415066 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

SNX17 293 Cell Lysate - 407118 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

SNX17 Overexpression Lysate (Denatured) - H00009784-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
SNX17 transfected lysate.

SNX17 Overexpression Lysate (Native) - NBP2-07282 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: SNX17 Overexpression Lysate (Adult Normal) [NBP2-07282] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SNX17.

SNX17 Over-expression Lysate Product - GWB-1FFDFA from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Panoply™ Human SNX17 Knockdown Stable Cell Line - CSC-DC014849 from Creative biogene

Category Cell Line
Species Human

Human SNX17 Knockout Cell Line-HeLa - CSC-RT1302 from Creative biogene

Category Cell Line
Species Human

SNX17 KO Cell Lysate-HeLa - CLKO-1154 from Creative biogene

Category Cell Lysate
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