SNX17

Gene Symbol SNX17
Entrez Gene 9784
Alt Symbol -
Species Human
Gene Type protein-coding
Description sorting nexin 17
Other Description sorting nexin-17
Swissprots Q53HN7 Q6IAS3 B4DQM7 Q15036
Accessions AAY14844 CAC12897 CAH05526 EAX00584 EAX00585 EAX00586 Q15036 AK129689 AK222543 BAD96263 AK293252 BAG56784 AK293464 BAG56959 AK295278 BAG58262 AK297054 BAG59579 AK298620 BAG60799 AK298856 BAG60979 AK298869 BAG60989 AK300144 BAG61930 AK300641 BAG62330 AK307122 AK308487 AK309640 AK316373 BAH14744 BC002524 AAH02524 BC002610 AAH02610 BC014620 AAH14620 BC021108 BC032320 BC050590 AAH50590 BT007167 AAP35831 CR457081 CAG33362 D31764 BAA06542 DB177194 XM_011533203 XP_011531505 NM_001267059 NP_001253988 NM_001267060 NP_001253989 NM_001267061 NP_001253990 NM_014748 NP_055563 NR_049782 NR_049783 NR_049784 NR_049785 NR_049786 NR_049787 NR_049788
Function Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)). {ECO:0000269|PubMed:15121882, ECO:0000269|PubMed:15769472, ECO:0000269|PubMed:16712798, ECO:0000269|PubMed:19005208, ECO:0000269|PubMed:21512128, ECO:0000269|PubMed:22492727}.
Subcellular Location Cytoplasm. Early endosome. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.

SNX17 (H-10) - sc-166957 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SNX17 (H-10): sc-166957. Western blot analysis of SNX17 expression in ES-2 whole cell lysate.

SNX17 (E-12) - sc-166597 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SNX17 (E-12): sc-166597. Western blot analysis of SNX17 expression in non-transfected: sc-117752 (A) and mouse SNX17 transfected: sc-123694 (B) 293T whole cell lysates.

SNX17 (H-201) - sc-99028 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SNX17 (H-201): sc-99028. Western blot analysis of SNX17 expression in non-transfected: sc-117752 (A) and human SNX17 transfected: sc-116283 (B) 293T whole cell lysates.

SNX17 (D-10) - sc-166585 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SNX17 (D-10): sc-166585. Western blot analysis of SNX17 expression in non-transfected: sc-117752 (A) and mouse SNX17 transfected: sc-123694 (B) 293T whole cell lysates.

SNX17 (N-14) - sc-49127 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SNX17 (N-14): sc-49127. Western blot analysis of SNX17 expression in non-transfected: sc-117752 (A) and mouse SNX17 transfected: sc-123694 (B) 293T whole cell lysates.

SNX17 (P-14) - sc-49128 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SNX17 (P-14): sc-49128. Western blot analysis of SNX17 expression in non-transfected: sc-117752 (A) and human SNX17 transfected: sc-116283 (B) 293T whole cell lysates.

SNX17 (Y-20) - sc-49129 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SNX17 (Y-20): sc-49129. Western blot analysis of SNX17 expression in non-transfected: sc-117752 (A) and human SNX17 transfected: sc-116283 (B) 293T whole cell lysates.

Anti-SNX17 antibody - ab124232 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-SNX17 antibody (ab124232) at 1/100 dilution + 293 cell line lysate at 35 µg

Anti-SNX17 antibody - ab67599 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-SNX17 antibody (ab67599) at 1/500 dilutionLane 1 : SNX17 transfected 293T lysateLane 2 : Non transfected 293T lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-SNX17 Antibody (aa53-82, APC) - LS-C269876 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNX17 Antibody (aa53-82, AP) - LS-C269875 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNX17 Antibody (aa53-82, Biotin) - LS-C269877 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNX17 Antibody (aa53-82, FITC) - LS-C269878 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNX17 Antibody (aa53-82, Azide-free, HRP) - LS-C269879 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNX17 Antibody (aa52-82) - LS-C325250 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNX17 Antibody (aa53-82, PE) - LS-C269880 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNX17 Antibody (Internal) - LS-C345299 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of SNX17 Antibody with human U937 Whole Cell lysate.

Anti-SNX17 Antibody (aa53-82) - LS-C161366 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SNX17 Antibody western blot of 293 cell line lysates (35 ug/lane). The SNX17 antibody detected the SNX17 protein (arrow).

SNX17 Antibody - NBP1-92417 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: SNX17 Antibody [NBP1-92417] - Staining of human cell line A-431 shows localization to vesicles.

SNX17 Antibody - H00009784-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

SNX17 Antibody (2A3) - H00009784-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2A3
Western Blot: SNX17 Antibody (2A3) [H00009784-M01] - SNX17 monoclonal antibody (M01), clone 2A3. Analysis of SNX17 expression in human kidney.

Anti-SNX17 antibody produced in rabbit - HPA043867 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SNX17: <B>Cat. No. HPA043867</B>: Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.

Anti-SNX17 (201-215) antibody produced in rabbit - SAB1104665 from Sigma-Aldrich

Prices $285.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNX17 (72-85) antibody produced in rabbit - SAB1104664 from Sigma-Aldrich

Prices $285.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNX17 antibody produced in mouse - SAB1406880 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SNX17: <B>Cat. No. SAB1406880</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~51.7 kDa using SNX17 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.
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