SNX17

Gene Symbol SNX17
Entrez Gene 9784
Alt Symbol -
Species Human
Gene Type protein-coding
Description sorting nexin 17
Other Description sorting nexin-17
Swissprots Q53HN7 Q6IAS3 B4DQM7 Q15036
Accessions AAY14844 CAC12897 CAH05526 EAX00584 EAX00585 EAX00586 Q15036 AK129689 AK222543 BAD96263 AK293252 BAG56784 AK293464 BAG56959 AK295278 BAG58262 AK297054 BAG59579 AK298620 BAG60799 AK298856 BAG60979 AK298869 BAG60989 AK300144 BAG61930 AK300641 BAG62330 AK307122 AK308487 AK309640 AK316373 BAH14744 BC002524 AAH02524 BC002610 AAH02610 BC014620 AAH14620 BC021108 BC032320 BC050590 AAH50590 BT007167 AAP35831 CR457081 CAG33362 D31764 BAA06542 DB177194 XM_011533203 XP_011531505 NM_001267059 NP_001253988 NM_001267060 NP_001253989 NM_001267061 NP_001253990 NM_014748 NP_055563 NR_049782 NR_049783 NR_049784 NR_049785 NR_049786 NR_049787 NR_049788
Function Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)). {ECO:0000269|PubMed:15121882, ECO:0000269|PubMed:15769472, ECO:0000269|PubMed:16712798, ECO:0000269|PubMed:19005208, ECO:0000269|PubMed:21512128, ECO:0000269|PubMed:22492727}.
Subcellular Location Cytoplasm. Early endosome. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.

SNX17 CRISPR/Cas9 KO Plasmid (h) - sc-403452 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNX17 HDR Plasmid (h) - sc-403452-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNX17 Double Nickase Plasmid (h) - sc-403452-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNX17 Double Nickase Plasmid (h2) - sc-403452-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNX17 CRISPR Activation Plasmid (h) - sc-403452-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNX17 CRISPR Activation Plasmid (h2) - sc-403452-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNX17 Lentiviral Activation Particles (h) - sc-403452-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNX17 Lentiviral Activation Particles (h2) - sc-403452-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNX17 siRNA (h) - sc-61587 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SNX17 shRNA Plasmid (h) - sc-61587-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SNX17 shRNA (h) Lentiviral Particles - sc-61587-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU137061 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20295 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20295 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03310 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03310

SNX17 siRNA (Human) - CRH6546 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SNX17 - MBS8207701 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SNX17 (NM_014748.3) - SHH414644 from Creative biogene

Category siRNA
Species Reactivities Human

SNX17 shRNA Plasmid (Human) - CHH6546 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SNX17 miRNA 3'UTR clone - MiUTR3H-08088 from Creative biogene

Species Reactivities Human
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