AQP2

Gene Symbol	AQP2
Entrez Gene	359
Alt Symbol	AQP-CD, WCH-CD
Species	Human
Gene Type	protein-coding
Description	aquaporin 2 (collecting duct)
Other Description	ADH water channel|AQP-2|aquaporin-2|aquaporin-CD|collecting duct water channel protein|water channel protein for renal collecting duct|water-channel aquaporin 2
Swissprots	P41181 Q9UD68
Accessions	AAD14825 AAD38692 AAK55747 BAA06632 CAA82627 EAW58109 P41181 AI792401 AK055824 AK225940 BC042496 AAH42496 CR542024 CAG46821 S73196 AAB31999 S73197 AAB31998 NM_000486 NP_000477
Function	Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
Subcellular Location	Apical cell membrane {ECO:0000269|PubMed:12194985}; Multi-pass membrane protein {ECO:0000269|PubMed:12194985}. Basolateral cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:12194985}; Multi- pass membrane protein {ECO:0000269|PubMed:12194985}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:12194985}; Multi-pass membrane protein {ECO:0000269|PubMed:12194985}. Note=Shuttles from vesicles to the apical membrane. Vasopressin-regulated phosphorylation is required for translocation to the apical cell membrane. PLEKHA8/FAPP2 is required to transport AQP2 from the TGN to sites where AQP2 is phosphorylated.
Tissue Specificity	Expressed in renal collecting tubules.
Top Pathways	Vasopressin-regulated water reabsorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rat AQP2 / Aquaporin 2 ELISA Kit (Sandwich ELISA) - LS-F4052 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.235 ng/ml Range 0.313-20 ng/ml

Human AQP2 / Aquaporin 2 ELISA Kit (Sandwich ELISA) - LS-F4051 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 0.313 ng/ml Range 0.313-20 ng/ml

Human AQP2 ELISA Kit - abx150728 from Abbexa Category ELISA Kit Sensitivity 0.114 ng/ml Range 0.313 ng/ml - 20 ng/ml

Aquaporin 2, AQP-2, Human, ELISA Kit - E-EL-H0488 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.188 Range 0.313-20ng/mL

Aquaporin 2, AQP-2, Human, ELISA Kit - CSB-E08242h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 3.9 pg/ml Range 15.6 pg/ml-1000 pg/ml

Aquaporin 2, Collecting Duct (AQP2), Human, ELISA Kit - SEA580Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 0.122ng/mL Range 0.312-20ng/mL

Aquaporin-2, AQP2, Human, ELISA Kit - E0580h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

Aquaporin 2, AQP-2, Mouse, ELISA Kit - E-EL-M0148 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.938 Range 1.563-100ng/mL

Aquaporin 2, AQP-2, Rabbit, ELISA Kit - E-EL-RB0247 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Aquaporin 2, AQP-2, Chicken, ELISA Kit - E-EL-Ch1753 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Aquaporin 2, AQP-2, Porcine, ELISA Kit - E-EL-P0360 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.188 Range 0.313-20ng/mL

Aquaporin 2, AQP-2, Sheep, ELISA Kit - E-EL-S0999 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Aquaporin 2, AQP-2, Guinea Pig, ELISA Kit - E-EL-GP0146 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Aquaporin 2, AQP-2, Monkey, ELISA Kit - E-EL-MK1899 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.188 Range 0.313-20ng/mL

Human AQP-2 ELISA Kit - HA0472 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine AQP2 ELISA Kit - AA0472 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Aquaporin 2 (Phospho-Ser256) Colorimetric Cell-Based ELISA - CBP1870 from Assay Biotechnology Category ELISA Kit Prices $450.00 Sizes 2 x 96 tests Range > 5000 Cells

ELISA Kit for Aquaporin 2, Collecting Duct (AQP2) - SEA580Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.112ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Aquaporin 2, Collecting Duct (AQP2) - SEA580Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.235ng/mL. Range 0.625-40ng/mL The standard curve concentrations used for the ELISA’s were 40ng/mL, 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL

AQP2 (Human) ELISA Kit - DEIA3172 from Creative Diagnostics Category ELISA Kit Sensitivity The minimum detectable dose of human AQP-2 is typically less than 0.039 ng/mL. Range 0.156-10 ng/mL. The standard curve concentrations used for the ELISA's were 10 ng/mL, 5 ng/mL, 2.5 ng/mL, 1.25 ng/mL, 0.625 ng/mL, 0.312 ng/mL, 0.156 ng/mL.

Human AQP-2(Aquaporin 2) ELISA Kit - E-EL-H0488 from Elabscience Category ELISA Kit Sensitivity 0.19 ng/mL Range 0.31—20 ng/mL

Human AQP-2 (Aquaporin 2) CLIA Kit - E-CL-H0398 from Elabscience Category CLIA Kit Sensitivity 46.88 pg/mL Range Average Recovery (%)

AQP-2, ELISA Kit - MBS2503453 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.875ng/mL Range 3.125-200ng/mL

AQP-2, ELISA Kit - MBS2507574 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313-20ng/mL

AQP-2, ELISA Kit - MBS2508109 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 9.375ng/mL Range 15.625-1000ng/mL

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