NRG2

Gene Symbol	NRG2
Entrez Gene	9542
Alt Symbol	DON1, HRG2, NTAK
Species	Human
Gene Type	protein-coding
Description	neuregulin 2
Other Description	divergent of neuregulin-1\|neural- and thymus-derived activator for ErbB kinases\|pro-NRG2\|pro-neuregulin-2, membrane-bound isoform
Swissprots	O14511
Accessions	AAF28848 AAF28849 AAF28850 AAF28851 AAF28852 AAF28853 EAW62078 EAW62080 EAW62081 EAW62082 EAW62083 EAW62084 EAW62085 EAW62086 EAW62087 O14511 AB005060 BAA23417 AI271427 AK124504 BAG54044 BC103983 AAI03984 BC103984 AAI03985 BC114333 AAI14334 BC114334 AAI14335 BC166615 AAI66615 DA090538 U92987 XM_005268533 XP_005268590 XM_006714808 XP_006714871 XM_006714810 XP_006714873 XM_011537710 XP_011536012 XM_011537711 XP_011536013 XM_011537712 XP_011536014 XM_011537713 XP_011536015 XR_944342 NM_001184935 NP_001171864 NM_004883 NP_004874 NM_013981 NP_053584 NM_013982 NP_053585 NM_013983 NP_053586 NM_013984 NM_013985
Function	Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. May also promote the heterodimerization with the EGF receptor.
Subcellular Location	Pro-neuregulin-2, membrane-bound isoform: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Does not seem to be active. {ECO:0000250}.
Tissue Specificity	Restricted to the cerebellum in the adult.
Top Pathways	ErbB signaling pathway

Neuregulin-2 (A-12) - sc-398594 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

Neuregulin-2 (A-12): sc-398594. Western blot analysis of Neuregulin-2 expression in human brain tissue extract.

Neuregulin-2 (H-8) - sc-390646 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

Neuregulin-2 (H-8): sc-390646. Western blot analysis of human recombinant Neuregulin-2 fusion protein.

Neuregulin-2 (G-13) - sc-34219 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Neuregulin-2 (G-13): sc-34219. Western blot analysis of human recombinant Neuregulin-2 fusion protein.

Neuregulin-2 (H-130) - sc-67001 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

Neuregulin-2 (L-15) - sc-34220 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Neuregulin-2 (L-15): sc-34220. Western blot analysis of human recombinant Neuregulin-2 fusion protein.

Neuregulin-2 (S-17) - sc-34218 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Neuregulin-2 (S-17): sc-34218. Western blot analysis of human recombinant Neuregulin-2 fusion protein.

Anti-NRG2 antibody - ab104474 from Abcam

Host	Rabbit
Clonality	Polyclonal

Anti-NRG2 antibody - ab60088 from Abcam

Prices	$359.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Ab60088 (1/50-1/100) staining human NRG2 in human cancer tissue by immunohistochemistry using formalin fixed, paraffin embedd tissue. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. HC = hepatocarcinoma.

Anti-NRG2 antibody - ab56746 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Western blot against tagged recombinant protein immunogen using ab56746 NRG2 antibody at 1ug/ml.

Anti-NRG2 antibody - ab131037 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-NRG2 antibody - ab190677 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NRG2 antibody (ab190677) at 1/500 dilution + HT29 cell extracts at 30 µg

Anti-NRG2 Antibody (aa358-389) - LS-C100469 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NRG2 Antibody (aa358-389, AP) - LS-C280056 from LifeSpan Bioscience

Prices	$515.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NRG2 Antibody (aa358-389, APC) - LS-C280059 from LifeSpan Bioscience

Prices	$515.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NRG2 Antibody (aa358-389, Biotin) - LS-C280060 from LifeSpan Bioscience

Prices	$515.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NRG2 Antibody (aa358-389, FITC) - LS-C280061 from LifeSpan Bioscience

Prices	$515.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NRG2 Antibody (aa358-389, Azide-free, HRP) - LS-C280062 from LifeSpan Bioscience

Prices	$515.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NRG2 Antibody (aa358-389, PE) - LS-C280063 from LifeSpan Bioscience

Prices	$515.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NRG2 Antibody (aa101-211, Biotin) - LS-C298155 from LifeSpan Bioscience

Prices	$435.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-NRG2 Antibody (aa101-211, FITC) - LS-C302676 from LifeSpan Bioscience

Prices	$455.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-NRG2 Antibody (Internal) - LS-C323451 from LifeSpan Bioscience

Prices	$415.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NRG2 Antibody (aa834-850) - LS-C328013 from LifeSpan Bioscience

Prices	$345.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NRG2 Antibody (clone 4D6) - LS-C139314 from LifeSpan Bioscience

Prices	$355.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	4D6

Detection limit for recombinant GST tagged NRG2 is approximately 3 ng/ml as a capture antibody.

Anti-NRG2 Antibody (aa289-306) - LS-C312792 from LifeSpan Bioscience

Prices	$305.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

WB of NRG2 antibody. Lane 1: Rat Liver Tissue Lysate. Lane 2: COLO320 cell Lysate. Lane 3: SMMC cell Lysate. Lane 4: SW620 cell Lysate.

Anti-NRG2 Antibody (aa101-211) - LS-C295576 from LifeSpan Bioscience

Prices	$405.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Search more