DENND1B

Gene Symbol DENND1B
Entrez Gene 163486
Alt Symbol C1ORF18, C1orf218, FAM31B
Species Human
Gene Type protein-coding
Description DENN/MADD domain containing 1B
Other Description DENN domain-containing protein 1B|connecdenn 2|family with sequence similarity 31, member B
Swissprots Q8TBE6 Q6P3S1 Q5T3B8 Q9H774 Q8NDT1 Q9NXU2 Q5T3B9 Q6B0I8 B5MD89 Q5T3C1 D3PFD5 Q5TAI8
Accessions CCQ43112 EAW91278 EAW91279 EAW91280 EAW91281 EAW91282 EAW91283 EAW91284 EAW91285 Q6P3S1 AI692985 AK000061 BAA90918 AK024832 BAB15024 AK091207 BAG52307 AK093982 AL831839 CAD38548 BC016588 AAH16588 BC022561 AAH22561 BC063456 BC063877 AAH63877 BC074735 AAH74735 BK006960 DAA12502 BP220095 DA495773 DQ892398 ABM83324 DQ895613 ABM86539 H19092 XM_005244931 XP_005244988 XM_005244932 XP_005244989 XM_006711192 XP_006711255 XM_006711193 XP_006711256 XM_006711194 XP_006711257 XM_011509246 XP_011507548 XM_011509247 XP_011507549 XM_011509248 XP_011507550 XM_011509249 XP_011507551 XM_011509250 XP_011507552 XM_011509251 XP_011507553 NM_001142795 NM_019049 NM_001195215 NP_001182144 NM_001195216 NP_001182145 NM_001300858 NP_001287787 NM_144977 NP_659414 NR_125340
Function Guanine nucleotide exchange factor (GEF) for RAB35. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. May play a role in clathrin- mediated endocytosis. {ECO:0000269|PubMed:20154091, ECO:0000269|PubMed:20937701}.
Subcellular Location Cytoplasm, cytosol {ECO:0000250}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000250}.
Tissue Specificity Highly expressed in dendritic and natural killer cells and at lower levels in other myeloid lineage cells and in pituitary. Significantly up-regulated in effector memory T- cells as compared with naive T-cells. {ECO:0000269|PubMed:20032318}.

DENND1B (E-16) - sc-240303 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

DENND1B (S-15) - sc-240305 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-DENND1B antibody - ab187903 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DENND1B antibody (ab187903) at 1/100 dilutionLane 1 : Human cell line RT-4Lane 2 : Human cell line U-251MG spdeveloped using the ECL technique

Anti-DENND1B Antibody (aa46-76, APC) - LS-C234526 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DENND1B Antibody (aa46-76, AP) - LS-C234525 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DENND1B Antibody (aa46-76, Biotin) - LS-C234527 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DENND1B Antibody (aa46-76, Azide-free, HRP) - LS-C249815 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DENND1B Antibody (aa46-76, FITC) - LS-C234528 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DENND1B Antibody (aa46-76, PE) - LS-C234530 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DENND1B Antibody (aa46-76) - LS-C320804 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DENND1B Antibody (aa39-68) - LS-C167360 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
DENND1B antibody immunohistochemistry of formalin-fixed and paraffin-embedded human lymph tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-DENND1B Antibody (aa1-272) - LS-C185868 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescence of paraformaldehyde-fixed HeLa using DENND1B antibody at 1:200 dilution.

Anti-DENND1B Antibody (aa144-193) IHC-plus™ - LS-B5833 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-DENND1B antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5833 concentration 5 ug/ml.

Anti-DENND1B Antibody (aa108-157) IHC-plus™ - LS-B5832 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-DENND1B antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5832 concentration 5 ug/ml.

DENND1B Antibody - NBP1-32715 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DENND1B Antibody [NBP1-32715] - Sample (30 ug of whole cell lysate)A: MOLT4 7. 5% SDS PAGE, antibody diluted at 1:1000.

DENND1B Antibody - NBP1-69245 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DENND1B Antibody - NBP1-69231 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DENND1B Antibody - H00163486-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot analysis of DENND1B expression in transfected 293T cell line by DENND1B MaxPab polyclonal antibody. Lane 1: DENND1B transfected lysate (43.56 KDa). Lane 2: Non-transfected lysate.

DENND1B Antibody - H00163486-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

DENND1B Polyclonal Antibody - bs-8254R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DENND1B antibody produced in rabbit - HPA042586 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-DENND1B: <B>Cat. No. HPA042586</B>: Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells.

Anti-DENND1B antibody produced in rabbit - HPA045494 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-DENND1B: <B>Cat. No. HPA045494</B>: Immunohistochemical staining of human oral mucosa shows moderate nuclear positivity in squamous epithelial cells.

Anti-DENND1B (ab1) antibody produced in rabbit - SAB2100561 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-DENND1B (ab1): <B>Cat. No.SAB2100561</B>: DENND1B in Fetal Muscle tissue lysate with DENND1B antibody at 1.0 μg/mL.

DENND1B antibody - N-terminal region (ARP52770_P050) - ARP52770_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DENND1B antibody - middle region (ARP52771_P050) - ARP52771_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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