DENND1B

Gene Symbol DENND1B
Entrez Gene 163486
Alt Symbol C1ORF18, C1orf218, FAM31B
Species Human
Gene Type protein-coding
Description DENN/MADD domain containing 1B
Other Description DENN domain-containing protein 1B|connecdenn 2|family with sequence similarity 31, member B
Swissprots Q8TBE6 Q6P3S1 Q5T3B8 Q9H774 Q8NDT1 Q9NXU2 Q5T3B9 Q6B0I8 B5MD89 Q5T3C1 D3PFD5 Q5TAI8
Accessions CCQ43112 EAW91278 EAW91279 EAW91280 EAW91281 EAW91282 EAW91283 EAW91284 EAW91285 Q6P3S1 AI692985 AK000061 BAA90918 AK024832 BAB15024 AK091207 BAG52307 AK093982 AL831839 CAD38548 BC016588 AAH16588 BC022561 AAH22561 BC063456 BC063877 AAH63877 BC074735 AAH74735 BK006960 DAA12502 BP220095 DA495773 DQ892398 ABM83324 DQ895613 ABM86539 H19092 XM_005244931 XP_005244988 XM_005244932 XP_005244989 XM_006711192 XP_006711255 XM_006711193 XP_006711256 XM_006711194 XP_006711257 XM_011509246 XP_011507548 XM_011509247 XP_011507549 XM_011509248 XP_011507550 XM_011509249 XP_011507551 XM_011509250 XP_011507552 XM_011509251 XP_011507553 NM_001142795 NM_019049 NM_001195215 NP_001182144 NM_001195216 NP_001182145 NM_001300858 NP_001287787 NM_144977 NP_659414 NR_125340
Function Guanine nucleotide exchange factor (GEF) for RAB35. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. May play a role in clathrin- mediated endocytosis. {ECO:0000269|PubMed:20154091, ECO:0000269|PubMed:20937701}.
Subcellular Location Cytoplasm, cytosol {ECO:0000250}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000250}.
Tissue Specificity Highly expressed in dendritic and natural killer cells and at lower levels in other myeloid lineage cells and in pituitary. Significantly up-regulated in effector memory T- cells as compared with naive T-cells. {ECO:0000269|PubMed:20032318}.

DENND1B CRISPR/Cas9 KO Plasmid (h) - sc-414864 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DENND1B HDR Plasmid (h) - sc-414864-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DENND1B Double Nickase Plasmid (h) - sc-414864-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DENND1B Double Nickase Plasmid (h2) - sc-414864-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DENND1B CRISPR Activation Plasmid (h) - sc-414864-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DENND1B CRISPR Activation Plasmid (h2) - sc-414864-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DENND1B Lentiviral Activation Particles (h) - sc-414864-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DENND1B Lentiviral Activation Particles (h2) - sc-414864-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DENND1B siRNA (h) - sc-88450 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DENND1B shRNA Plasmid (h) - sc-88450-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DENND1B shRNA (h) Lentiviral Particles - sc-88450-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU116911 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7136 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7136 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

DENND1B siRNA (Human) - CRJ5991 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DENND1B - MBS826962 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DENND1B (NM_001195215.1) - SHH277013 from Creative biogene

Category siRNA
Species Reactivities Human

Human DENND1B siRNA - orb276492 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DENND1B shRNA Plasmid (Human) - CHJ5991 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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