Gene Symbol | UST |
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Entrez Gene | 10090 |
Alt Symbol | 2OST |
Species | Human |
Gene Type | protein-coding |
Description | uronyl-2-sulfotransferase |
Other Description | dermatan/chondroitin sulfate 2-sulfotransferase|uronyl 2-sulfotransferase |
Swissprots | B2RCX6 Q9Y2C2 |
Accessions | EAW47812 Q9Y2C2 AB020316 BAA77510 AI570697 AJ420554 AK292922 BAF85611 AK315320 BAG37723 BC093668 AAH93668 BC093694 AAH93694 CA842761 DB496757 XM_005266790 XP_005266847 XM_011535376 XP_011533678 XM_011535377 XP_011533679 XM_011535378 XP_011533680 XR_942249 NM_005715 NP_005706 |
Function | Sulfotransferase that catalyzes the transfer of sulfate to the position 2 of uronyl residues. Has mainly activity toward iduronyl residues in dermatan sulfate, and weaker activity toward glucuronyl residues of chondroitin sulfate. Has no activity toward desulfated N-resulfated heparin. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:10187838}. |
Top Pathways | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate |
UST (S-12) - sc-132489 from Santa Cruz Biotechnology
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UST (D-20) - sc-102151 from Santa Cruz Biotechnology
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Anti-uronyl 2 sulfotransferase antibody - ab137624 from Abcam
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Anti-uronyl 2 sulfotransferase antibody - ab65555 from Abcam
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Anti-uronyl 2 sulfotransferase antibody - ab130597 from Abcam
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Anti-UST Antibody (aa291-319, APC) - LS-C242518 from LifeSpan Bioscience
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Anti-UST Antibody (aa291-319, AP) - LS-C242516 from LifeSpan Bioscience
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Anti-UST Antibody (aa291-319, FITC) - LS-C242520 from LifeSpan Bioscience
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Anti-UST Antibody (aa291-319, Biotin) - LS-C242519 from LifeSpan Bioscience
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Anti-UST Antibody (aa291-319, PE) - LS-C242523 from LifeSpan Bioscience
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Anti-UST Antibody (aa291-319, Azide-free, HRP) - LS-C247208 from LifeSpan Bioscience
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Anti-UST Antibody (aa290-319) - LS-C326240 from LifeSpan Bioscience
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Anti-UST Antibody (aa71-120) - LS-C116332 from LifeSpan Bioscience
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Anti-UST Antibody (aa291-319) - LS-C157336 from LifeSpan Bioscience
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Anti-UST Antibody (aa301-350) - LS-C80912 from LifeSpan Bioscience
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UST Antibody - NBP1-60042 from Novus Biologicals
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UST Antibody - NBP1-89383 from Novus Biologicals
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UST Antibody - NBP1-32585 from Novus Biologicals
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Anti-UST antibody produced in rabbit - AV46637 from Sigma-Aldrich
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Anti-UST antibody produced in rabbit - HPA032022 from Sigma-Aldrich
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UST antibody - C-terminal region (ARP46637_T100) - ARP46637_T100 from Aviva Systems Biology
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UST antibody - N-terminal region (ARP46638_P050) - ARP46638_P050 from Aviva Systems Biology
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UST-Antibody-C-term - AP17272b from Abgent, a WuXi AppTec company
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UST Antibody - C-terminal region (OAAB12703) - OAAB12703 from Aviva Systems Biology
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UST antibody - 70R-6963 from Fitzgerald
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