Gene Symbol | UST |
---|---|
Entrez Gene | 10090 |
Alt Symbol | 2OST |
Species | Human |
Gene Type | protein-coding |
Description | uronyl-2-sulfotransferase |
Other Description | dermatan/chondroitin sulfate 2-sulfotransferase|uronyl 2-sulfotransferase |
Swissprots | B2RCX6 Q9Y2C2 |
Accessions | EAW47812 Q9Y2C2 AB020316 BAA77510 AI570697 AJ420554 AK292922 BAF85611 AK315320 BAG37723 BC093668 AAH93668 BC093694 AAH93694 CA842761 DB496757 XM_005266790 XP_005266847 XM_011535376 XP_011533678 XM_011535377 XP_011533679 XM_011535378 XP_011533680 XR_942249 NM_005715 NP_005706 |
Function | Sulfotransferase that catalyzes the transfer of sulfate to the position 2 of uronyl residues. Has mainly activity toward iduronyl residues in dermatan sulfate, and weaker activity toward glucuronyl residues of chondroitin sulfate. Has no activity toward desulfated N-resulfated heparin. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:10187838}. |
Top Pathways | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate |
UST CRISPR/Cas9 KO Plasmid (h) - sc-408519 from Santa Cruz Biotechnology
|
||||||||
UST HDR Plasmid (h) - sc-408519-HDR from Santa Cruz Biotechnology
|
||||||||
UST Double Nickase Plasmid (h) - sc-408519-NIC from Santa Cruz Biotechnology
|
||||||||
UST Double Nickase Plasmid (h2) - sc-408519-NIC-2 from Santa Cruz Biotechnology
|
||||||||
UST CRISPR Activation Plasmid (h) - sc-408519-ACT from Santa Cruz Biotechnology
|
||||||||
UST CRISPR Activation Plasmid (h2) - sc-408519-ACT-2 from Santa Cruz Biotechnology
|
||||||||
UST Lentiviral Activation Particles (h) - sc-408519-LAC from Santa Cruz Biotechnology
|
||||||||
UST Lentiviral Activation Particles (h2) - sc-408519-LAC-2 from Santa Cruz Biotechnology
|
||||||||
UST siRNA (h) - sc-95159 from Santa Cruz Biotechnology
|
||||||||
UST shRNA Plasmid (h) - sc-95159-SH from Santa Cruz Biotechnology
|
||||||||
UST shRNA (h) Lentiviral Particles - sc-95159-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU025471 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN22610 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22610 from Sigma-Aldrich
|
||||||||
UST siRNA (Human) - CRH6799 from Cohesion Biosciences
|
||||||||
UST - MBS8217343 from MyBioSource
|
||||||||
shRNA set against Human UST (NM_005715.2) - SHH441852 from Creative biogene
|
||||||||
Human UST siRNA - orb267301 from Biorbyt
|
||||||||
UST shRNA Plasmid (Human) - CHH6799 from Cohesion Biosciences
|
||||||||
UST miRNA 3'UTR clone - MiUTR4H-TG09726 from Creative biogene
|