Gene Symbol | MPP1 |
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Entrez Gene | 4354 |
Alt Symbol | AAG12, DXS552E, EMP55, MRG1, PEMP |
Species | Human |
Gene Type | protein-coding |
Description | membrane protein, palmitoylated 1, 55kDa |
Other Description | 55 kDa erythrocyte membrane protein|aging-associated gene 12|erythrocyte membrane protein p55|migration-related gene 1|p55|palmitoylated erythrocyte membrane protein |
Swissprots | B4DZV5 Q2TSB6 Q5J7V5 G3XAI1 Q00013 |
Accessions | AAA60060 AAD14835 EAW72655 EAW72656 EAW72657 EAW72658 EAW72659 EAW72660 Q00013 AK093702 AK223396 BAD97116 AK290246 BAF82935 AK303111 BAG64217 AK304538 BAG65337 AK310681 AK311541 AK312296 BAG35223 AK315957 BAH14328 AY423731 AAS00494 AY634686 AAV35469 BC002392 AAH02392 DA074686 DQ891247 ABM82173 DQ894572 ABM85498 M64925 AAA60059 XM_011531167 XP_011529469 XM_011531168 XP_011529470 XM_011531169 XP_011529471 NM_001166460 NP_001159932 NM_001166461 NP_001159933 NM_001166462 NP_001159934 NM_002436 NP_002427 |
Function | Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Lipid-anchor. Cell projection, stereocilium {ECO:0000250}. Note=Colocalizes with WHRN at stereocilium tip during hair cell development (By similarity). Colocalizes with MPP5 in the retina, at the outer limiting membrane (OLM). Colocalizes with WHRN in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium (CC). Colocalizes with NF2 in non- myelin-forming Schwann cells. {ECO:0000250}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:17584769}. |
p55 (A-4) - sc-376480 from Santa Cruz Biotechnology
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p55 (A-7) - sc-374506 from Santa Cruz Biotechnology
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p55 (C-16) - sc-13493 from Santa Cruz Biotechnology
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p55 (N-19) - sc-13490 from Santa Cruz Biotechnology
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p55 (H-57) - sc-292285 from Santa Cruz Biotechnology
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p55 (51-B) - sc-130381 from Santa Cruz Biotechnology
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Anti-MPP1 antibody - ab55464 from Abcam
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Anti-MPP1 antibody - ab172047 from Abcam
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Anti-MPP1 antibody - ab107553 from Abcam
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Anti-MPP1 antibody [EPR5864] - ab133500 from Abcam
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Anti-MPP1 antibody [EPR5865] - ab108528 from Abcam
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Anti-MPP1 Antibody (aa1-304) - LS-C186228 from LifeSpan Bioscience
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Anti-MPP1 Antibody (C-Terminus) - LS-C345684 from LifeSpan Bioscience
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Anti-MPP1 Antibody - LS-C334622 from LifeSpan Bioscience
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Anti-MPP1 Antibody (aa1-50) - LS-C291069 from LifeSpan Bioscience
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Anti-MPP1 Antibody (aa301-327) - LS-C164610 from LifeSpan Bioscience
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Anti-MPP1 Antibody (clone 1E11-1G11) - LS-C197697 from LifeSpan Bioscience
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Anti-MPP1 Antibody (Internal, clone EPR5865) - LS-C138543 from LifeSpan Bioscience
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Anti-MPP1 Antibody (aa301-327, AP) - LS-C223315 from LifeSpan Bioscience
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Anti-MPP1 Antibody (aa24-73) - LS-C151673 from LifeSpan Bioscience
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Anti-MPP1 Antibody (Internal, clone EPR5864) - LS-C138642 from LifeSpan Bioscience
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Anti-MPP1 Antibody (aa301-327, Biotin) - LS-C223317 from LifeSpan Bioscience
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Anti-MPP1 Antibody (aa301-327, APC) - LS-C223316 from LifeSpan Bioscience
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Anti-MPP1 Antibody (aa301-327, Azide-free, HRP) - LS-C223319 from LifeSpan Bioscience
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Anti-MPP1 Antibody (aa301-327, FITC) - LS-C223318 from LifeSpan Bioscience
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