Gene Symbol | CAV1 |
---|---|
Entrez Gene | 281040 |
Alt Symbol | - |
Species | Bovine |
Gene Type | protein-coding |
Description | caveolin 1, caveolae protein, 22kDa |
Other Description | caveolin-1 |
Swissprots | P79132 Q5PX19 A4D7R5 |
Accessions | AAR16256 DAA30606 P79132 AY823915 AAV83691 BC103050 AAI03051 U86639 AAB47274 XM_005205391 XP_005205448 XM_005205392 XP_005205449 XM_010804191 XP_010802493 XM_010804192 XP_010802494 NM_174004 NP_776429 |
Function | Involved in the costimulatory signal essential for T- cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. May act as a scaffolding protein within caveolar membranes. Interacts directly with G- protein alpha subunits and can functionally regulate their activity. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway (By similarity). {ECO:0000250}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Membrane, caveola {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Membrane raft {ECO:0000250}. Note=Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity). {ECO:0000250}. |
Top Pathways | Focal adhesion, Endocytosis, Bacterial invasion of epithelial cells, Proteoglycans in cancer |
Caveolin-1, CAV1, Bovine, ELISA Kit - E0214b from ARP American Research Products
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Bovine CAV1 ELISA Kit - BC0414 from NeoScientific
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Bovine Cav-1 ELISA Kit - BC0707 from NeoScientific
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Bovine Caveolin 1 ELISA - E11C0407 from BlueGene Biotech
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Cow CAV1 ELISA Kit - abx570490 from Abbexa
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Bovine CAV1 ELISA Kit - E077463 from Biobool
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Bovine Cav-1 ELISA Kit - EBC0707 from ABclonal
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Bovine CAV1 ELISA Kit - EBC0414 from ABclonal
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Bovine Caveolin-1 ELISA Kit - EK1496 from Signalway Antibody
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Caveolin 1 (CAV1), ELISA Kit - MBS456383 from MyBioSource
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Caveolin-1, ELISA Kit - MBS2884641 from MyBioSource
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Caveolin-1, ELISA Kit - MBS9425358 from MyBioSource
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