| Gene Symbol | CAV1 |
|---|---|
| Entrez Gene | 281040 |
| Alt Symbol | - |
| Species | Bovine |
| Gene Type | protein-coding |
| Description | caveolin 1, caveolae protein, 22kDa |
| Other Description | caveolin-1 |
| Swissprots | P79132 Q5PX19 A4D7R5 |
| Accessions | AAR16256 DAA30606 P79132 AY823915 AAV83691 BC103050 AAI03051 U86639 AAB47274 XM_005205391 XP_005205448 XM_005205392 XP_005205449 XM_010804191 XP_010802493 XM_010804192 XP_010802494 NM_174004 NP_776429 |
| Function | Involved in the costimulatory signal essential for T- cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. May act as a scaffolding protein within caveolar membranes. Interacts directly with G- protein alpha subunits and can functionally regulate their activity. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway (By similarity). {ECO:0000250}. |
| Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Membrane, caveola {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Membrane raft {ECO:0000250}. Note=Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity). {ECO:0000250}. |
| Top Pathways | Focal adhesion, Endocytosis, Bacterial invasion of epithelial cells, Proteoglycans in cancer |
Recombinant Bovine Caveolin-1(CAV1) - CSB-YP004571BO CSB-EP004571BO CSB-BP004571BO CSB-MP004571BO from Cusabio
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Caveolin-1 (CAV1), Recombinant Protein - MBS961088 from MyBioSource
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