Gene Symbol | IL1RL1 |
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Entrez Gene | 9173 |
Alt Symbol | DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1 |
Species | Human |
Gene Type | protein-coding |
Description | interleukin 1 receptor-like 1 |
Other Description | growth stimulation-expressed|homolog of mouse growth stimulation-expressed|interleukin 1 receptor-related protein|interleukin-1 receptor-like 1 |
Swissprots | A8K6B3 Q9ULV7 Q01638 B4E0I3 Q8NEJ3 Q9UQ44 Q53TU7 |
Accessions | AAY15047 BAA20539 EAX01795 Q01638 AB012701 BAA82405 AB029084 BAA85894 AK291578 BAF84267 AK303389 BAG64445 AL117622 AL553735 AM392936 CAL37814 BC012580 BC030975 AAH30975 BQ012352 D12763 BAA02233 DA884586 DB063031 EU181431 ABW33704 EU181432 ABW33705 XM_006712839 XP_006712902 XM_011512151 XP_011510453 NM_001282408 NP_001269337 NM_003856 NP_003847 NM_016232 NP_057316 NR_104167 NM_173459 |
Function | Receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function. {ECO:0000269|PubMed:16286016}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:11478810}; Single-pass type I membrane protein {ECO:0000269|PubMed:11478810}. |
Tissue Specificity | Highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. Isoform A is prevalently expressed in the lung, testis, placenta, stomach and colon. Isoform B is more abundant in the brain, kidney and the liver. Isoform C is not detected in brain, heart, liver, kidney and skeletal muscle. {ECO:0000269|PubMed:11478810}. |
E. coli ST2 full length protein - ab166883 from Abcam
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Human ST2 peptide - ab99882 from Abcam
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Human ST2 protein fragment - ab82985 from Abcam
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Human ST2 protein fragment - ab82990 from Abcam
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Mouse ST2 peptide - ab39855 from Abcam
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IL1RL1 Antibody Blocking Peptide - LS-E30083 from LifeSpan Bioscience
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IL1RL1 Antibody Blocking Peptide - LS-E17128 from LifeSpan Bioscience
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IL1RL1-Antibody-C-term-Blocking-Peptide - BP19457b from Abgent, a WuXi AppTec company
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Recombinant Human ST2/IL-1 R4 Fc Chimera, CF - 523-ST-100 from R&D Systems
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IL1RL1 Protein (OPPA01889) - OPPA01889 from Aviva Systems Biology
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Human IL1RL1 protein - orb246568 from Biorbyt
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IL1RL1 Blocking Peptide - 33R-8118 from Fitzgerald
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IL1RL1 protein (Fc Chimera) - 30R-3322 from Fitzgerald
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Human IL1RL1 Protein - abx067413 from Abbexa
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Human IL1RL1 Protein - abx067412 from Abbexa
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IL1RL1 / ST2 Control Peptide - AP30829CP-N from Acris Antibodies
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Interleukin-1 receptor-like 1, Human Recombinant - 228-10954-1 from RayBiotech
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Recombinant Human IL1R1 - 228-10954-2 from RayBiotech
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Recombinant Human IL1R1 - 228-10954-3 from RayBiotech
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Interleukin 1 Receptor Like Protein 1 (IL1RL1), Human - 20-9318 from ARP American Research Products
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Interleukin 1 Receptor Like Protein 1 (IL1RL1), Human - 20-9319 from ARP American Research Products
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ST2 Recombinant Protein - 96-427 from ProSci
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ST2 Recombinant Protein - 96-428 from ProSci
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IL1RL1 fusion protein - ag2555 from Proteintech Group
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IL1RL1 fusion protein - ag16697 from Proteintech Group
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