SLC5A12

Gene Symbol SLC5A12
Entrez Gene 159963
Alt Symbol SMCT2
Species Human
Gene Type protein-coding
Description solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
Other Description electroneutral sodium monocarboxylate cotransporter|low-affinity sodium-lactate cotransporter|sodium-coupled monocarboxylate transporter 2|sodium-iodide related cotransporter|solute carrier family 5 (sodium/glucose cotransporter), member 12|solute carrier family 5 member 12
Swissprots Q1EHB4 Q86UC7
Accessions EAW68293 EAW68294 EAW68295 Q1EHB4 AL049270 AW614338 AY299482 AAQ73572 BC029048 BC041454 AAH41454 BC049207 AAH49207 BM924715 CN370367 CR747563 XM_006718155 XP_006718218 XM_006718156 XP_006718219 XM_006718157 XP_006718220 XM_011519920 XP_011518222 XM_011519921 XP_011518223 XR_930845 NM_178498 NP_848593
Function Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter. Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D- hydroxybutyrate. May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May play also a role in monocarboxylates transport in the retina (By similarity). Mediates electroneutral uptake of lactate, with a stoichiometry of 2 Na(+) for each lactate (By similarity). {ECO:0000250}.
Subcellular Location Apical cell membrane {ECO:0000269|PubMed:17692818}; Multi-pass membrane protein {ECO:0000269|PubMed:17692818}. Note=Detected at the brush border membrane of the kidney. Colocalizes with viementin in Mueller cells (By similarity). {ECO:0000250}.

SLC5A12 CRISPR/Cas9 KO Plasmid (h) - sc-405626 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC5A12 HDR Plasmid (h) - sc-405626-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC5A12 Double Nickase Plasmid (h) - sc-405626-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC5A12 Double Nickase Plasmid (h2) - sc-405626-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC5A12 CRISPR Activation Plasmid (h) - sc-405626-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC5A12 CRISPR Activation Plasmid (h2) - sc-405626-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC5A12 Lentiviral Activation Particles (h) - sc-405626-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC5A12 Lentiviral Activation Particles (h2) - sc-405626-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC5A12 siRNA (h) - sc-96515 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SLC5A12 shRNA Plasmid (h) - sc-96515-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SLC5A12 shRNA (h) Lentiviral Particles - sc-96515-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SLC5A12 RNAi - H00159963-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU062781 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19661 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19661 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06497 from Sigma-Aldrich

Category miRNA

SLC5A12 siRNA (Human) - CRJ5893 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC5A12 - MBS8212773 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SLC5A12 (NM_178498.3) - SHH411676 from Creative biogene

Category siRNA
Species Reactivities Human

Human SLC5A12 siRNA - orb276394 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC5A12 shRNA Plasmid (Human) - CHJ5893 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SLC5A12 miRNA 3'UTR clone - MiUTR1H-09584 from Creative biogene

Species Reactivities Human
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