Gene Symbol | HEY1 |
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Entrez Gene | 23462 |
Alt Symbol | BHLHb31, CHF2, HERP2, HESR1, HRT-1, OAF1, hHRT1 |
Species | Human |
Gene Type | protein-coding |
Description | hes-related family bHLH transcription factor with YRPW motif 1 |
Other Description | HES-related repressor protein 1|HES-related repressor protein 2|basic helix-loop-helix protein OAF1|cardiovascular helix-loop-helix factor 2|class B basic helix-loop-helix protein 31|hairy and enhancer of split-related protein 1|hairy-related transcription factor 1|hairy/enhancer-of-split related with YRPW motif 1|hairy/enhancer-of-split related with YRPW motif protein 1 |
Swissprots | Q5TZS3 Q9NYP4 Q9Y5J3 Q8NAM2 B2R883 |
Accessions | CAB90212 EAW87066 Q9Y5J3 AF151522 AAD38967 AF176422 AAD51749 AF232239 AAF37297 AF254637 AAL06278 AF311883 AAG31156 AJ272214 CAB75715 AK074641 BAG51980 AK092437 BAC03890 AK226041 AK293646 BAG57100 AK307622 AK313271 BAG36080 BC001873 AAH01873 BP283540 BT020065 AAV38868 DA561783 JF432799 ADZ16016 R61374 NM_001040708 NP_001035798 NM_012258 NP_036390 NM_001282851 NP_001269780 |
Function | Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'- CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6. {ECO:0000269|PubMed:11095750, ECO:0000269|PubMed:15485867}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00380, ECO:0000255|PROSITE-ProRule:PRU00981}. |
Tissue Specificity | Expressed in the somitic mesoderm, the central nervous system, the kidney, the heart, nasal epithelium, and limbs. |
HRT1 (C-20) - sc-16424 from Santa Cruz Biotechnology
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HRT1 (H-120) - sc-28746 from Santa Cruz Biotechnology
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HRT1 (H-16) - sc-30948 from Santa Cruz Biotechnology
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HRT1 (P-20) - sc-30947 from Santa Cruz Biotechnology
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HRT1 (NB-A7) - sc-134362 from Santa Cruz Biotechnology
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Anti-HEY1 antibody - ab111723 from Abcam
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Anti-HEY1 antibody - ab57120 from Abcam
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Anti-HEY1 antibody - ab57121 from Abcam
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Anti-HEY1 Antibody (aa33-82) - LS-C206121 from LifeSpan Bioscience
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Anti-HEY1 Antibody (aa197-246) - LS-C170122 from LifeSpan Bioscience
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Anti-HEY1 Antibody (aa207-220) - LS-C7392 from LifeSpan Bioscience
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Anti-HEY1 Antibody - LS-C125695 from LifeSpan Bioscience
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Anti-HEY1 Antibody (aa121-221) - LS-C308223 from LifeSpan Bioscience
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Anti-HEY1 Antibody (aa180-229) - LS-C145431 from LifeSpan Bioscience
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Anti-HEY1 Antibody (aa215-264) - LS-C107603 from LifeSpan Bioscience
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Anti-HEY1 Antibody (C-Terminus) - LS-C345800 from LifeSpan Bioscience
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Anti-HEY1 Antibody (aa35-84) - LS-C107616 from LifeSpan Bioscience
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HEY1 Antibody - NBP2-27152 from Novus Biologicals
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HEY1 Antibody - NB100-75431 from Novus Biologicals
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HEY1 Antibody (3B3) - H00023462-M01 from Novus Biologicals
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HEY1 Antibody (1F11) - H00023462-M09 from Novus Biologicals
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HEY1 Antibody (2F10) - H00023462-M02 from Novus Biologicals
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HEY1 Antibody (1B9) - H00023462-M03 from Novus Biologicals
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HEY1 Antibody (1E10) - H00023462-M05 from Novus Biologicals
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HEY1 Antibody - NBP2-16818 from Novus Biologicals
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