Gene Symbol | HEY1 |
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Entrez Gene | 23462 |
Alt Symbol | BHLHb31, CHF2, HERP2, HESR1, HRT-1, OAF1, hHRT1 |
Species | Human |
Gene Type | protein-coding |
Description | hes-related family bHLH transcription factor with YRPW motif 1 |
Other Description | HES-related repressor protein 1|HES-related repressor protein 2|basic helix-loop-helix protein OAF1|cardiovascular helix-loop-helix factor 2|class B basic helix-loop-helix protein 31|hairy and enhancer of split-related protein 1|hairy-related transcription factor 1|hairy/enhancer-of-split related with YRPW motif 1|hairy/enhancer-of-split related with YRPW motif protein 1 |
Swissprots | Q5TZS3 Q9NYP4 Q9Y5J3 Q8NAM2 B2R883 |
Accessions | CAB90212 EAW87066 Q9Y5J3 AF151522 AAD38967 AF176422 AAD51749 AF232239 AAF37297 AF254637 AAL06278 AF311883 AAG31156 AJ272214 CAB75715 AK074641 BAG51980 AK092437 BAC03890 AK226041 AK293646 BAG57100 AK307622 AK313271 BAG36080 BC001873 AAH01873 BP283540 BT020065 AAV38868 DA561783 JF432799 ADZ16016 R61374 NM_001040708 NP_001035798 NM_012258 NP_036390 NM_001282851 NP_001269780 |
Function | Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'- CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6. {ECO:0000269|PubMed:11095750, ECO:0000269|PubMed:15485867}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00380, ECO:0000255|PROSITE-ProRule:PRU00981}. |
Tissue Specificity | Expressed in the somitic mesoderm, the central nervous system, the kidney, the heart, nasal epithelium, and limbs. |
Human HEY1 peptide - ab111660 from Abcam
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HEY1 Antibody Blocking Peptide - LS-E11400 from LifeSpan Bioscience
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HEY1 Antibody Blocking Peptide - LS-E11399 from LifeSpan Bioscience
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HEY1 Antibody Blocking Peptide - LS-E15257 from LifeSpan Bioscience
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HEY1 Antibody Blocking Peptide - LS-E15256 from LifeSpan Bioscience
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Recombinant Human HEY1 Protein - H00023462-P01 from Novus Biologicals
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Recombinant Human HEY1 Protein - H00023462-Q01 from Novus Biologicals
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HEY1 Recombinant Protein - GTX48046-PRO from GeneTex
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Hey1 Blocking Peptide - 33R-9951 from Fitzgerald
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HEY1 Blocking Peptide - 33R-1335 from Fitzgerald
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HEY1 Blocking Peptide - 33R-3822 from Fitzgerald
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HEY1 - H00023462-P01-10 from Acris Antibodies
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HEY1 - H00023462-P01-25 from Acris Antibodies
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HEY1 - H00023462-Q01-10 from Acris Antibodies
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HEY1 - H00023462-Q01-25 from Acris Antibodies
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HEY1 Recombinant Protein - XW-RP3109 from ProSci
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HEY1 fusion protein - ag13906 from Proteintech Group
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HEY1 fusion protein - Ag14094 from Proteintech Group
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Recombinant Human HEY1, His-tagged - HEY1-29230TH from Creative Biomart
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Recombinant Human HEY1, His-tagged - HEY1-1539H from Creative Biomart
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Recombinant Human Hairy/enhancer-of-split related with YRPW motif protein 1(HEY1) - CSB-YP896909HU CSB-EP896909HU CSB-BP896909HU CSB-MP896909HU from Cusabio
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HEY1 (transcript variant 2) - TP316696 from Acris Antibodies
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Recombinant Human Hairy/Enhancer-of-split related with YRPW motif 1 His - CRH213 from Cell Science
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HEY1 Recombinant Protein Antigen - NBP2-47436PEP from Novus Biologicals
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HEY1 Protein (OPPB00501) - OPPB00501 from Aviva Systems Biology
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