MEIOB

Gene Symbol MEIOB
Entrez Gene 254528
Alt Symbol C16orf73, gs129
Species Human
Gene Type protein-coding
Description meiosis specific with OB domains
Other Description meiosis-specific with OB domain-containing protein
Swissprots Q8N635 C9J0S1 Q96RY0 B1AK39
Accessions AAK61296 CAM28376 EAW85604 EAW85605 EAW85606 EAW85607 Q8N635 BC029829 AAH29829 CD300613 DB461414 DQ891299 ABM82225 DQ894483 ABM85409 NM_001163560 NP_001157032 NM_152764 NP_689977
Function Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Chromosome {ECO:0000250}. Note=Co-localizes with the RPA complex on meiotic chromosome axes. Accumulates on resected DNA. Localization is dependent on SPATA22 (By similarity). {ECO:0000250}.
Tissue Specificity In fetal gonads, specifically expressed in the ovary starting at the 14th weeks post fertilization. {ECO:0000269|PubMed:24068956}.

MEIOB CRISPR/Cas9 KO Plasmid (h) - sc-415202 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MEIOB HDR Plasmid (h) - sc-415202-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MEIOB Double Nickase Plasmid (h) - sc-415202-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MEIOB Double Nickase Plasmid (h2) - sc-415202-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C16orf73 CRISPR Activation Plasmid (h) - sc-415202-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MEIOB CRISPR Activation Plasmid (h2) - sc-415202-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MEIOB Lentiviral Activation Particles (h) - sc-415202-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MEIOB Lentiviral Activation Particles (h2) - sc-415202-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MEIOB siRNA (h) - sc-93168 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MEIOB shRNA Plasmid (h) - sc-93168-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MEIOB shRNA (h) Lentiviral Particles - sc-93168-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU113091 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4424 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4424 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01778 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01778

MEIOB siRNA (Human) - CRJ6687 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human C16orf73 (NM_152764.2) - SHH249714 from Creative biogene

Category siRNA
Species Reactivities Human

Human MEIOB siRNA - orb277188 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MEIOB shRNA Plasmid (Human) - CHJ6687 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MEIOB miRNA 3'UTR clone - MiUTR4H-TG01400 from Creative biogene

Species Reactivities Human
Search more