MEIOB

Gene Symbol	MEIOB
Entrez Gene	254528
Alt Symbol	C16orf73, gs129
Species	Human
Gene Type	protein-coding
Description	meiosis specific with OB domains
Other Description	meiosis-specific with OB domain-containing protein
Swissprots	Q8N635 C9J0S1 Q96RY0 B1AK39
Accessions	AAK61296 CAM28376 EAW85604 EAW85605 EAW85606 EAW85607 Q8N635 BC029829 AAH29829 CD300613 DB461414 DQ891299 ABM82225 DQ894483 ABM85409 NM_001163560 NP_001157032 NM_152764 NP_689977
Function	Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Chromosome {ECO:0000250}. Note=Co-localizes with the RPA complex on meiotic chromosome axes. Accumulates on resected DNA. Localization is dependent on SPATA22 (By similarity). {ECO:0000250}.
Tissue Specificity	In fetal gonads, specifically expressed in the ovary starting at the 14th weeks post fertilization. {ECO:0000269\|PubMed:24068956}.

Anti-C16orf73 antibody - ab150886 from Abcam

Prices	$443.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunofluorescent staining of Human cell line A-431 shows positivity in nucleus but not nucleoli, cytoplasm and centrosome. Recommended concentration of ab150886 1-4 µg/ml. Cells treated with PFA/Triton X-100.

Anti-C16orf73 antibody - ab150888 from Abcam

Prices	$443.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemical analysis of paraffin-embedded Human breast tissue labeling C16orf73 with ab150888 at 1/20 dilution.

Anti-C16orf73 Antibody (C-Terminus) - LS-C116620 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

C16orf73 antibody LS-C116620 Western blot of Fetal liver lysate.

Anti-C16orf73 Antibody (aa264-313) - LS-C187206 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of Human Uterus Tumor. MEIOB antibody dilution 1.0 ug/ml.

C16orf73 Antibody - NBP2-14384 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunocytochemistry/ Immunofluorescence: C16orf73 Antibody [NBP2-14384] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli, cytoplasm & centrosome.

C16orf73 Antibody - NBP1-70440 from Novus Biologicals

Prices	$139.00, $329.00
Sizes	20 µl, 100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: C16orf73 Antibody [NBP1-70440] - Human Liver cell lysate, concentration 0.2-1 ug/ml.

C16orf73 Antibody - NBP2-14385 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry: C16orf73 Antibody [NBP2-14385] - Staining of human breast shows strong cytoplasmic and membranous positivity in glandular cells.

Anti-MEIOB antibody produced in rabbit - HPA042161 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-C16orf73:<B>Cat. No. HPA042161</B>: Immunohistochemical staining of human pancreas shows moderate cytoplasmic positivity in exocrine glandular cells.

Anti-C16ORF73 antibody produced in rabbit - HPA042547 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-C16orf73:<B>Cat. No. HPA042547</B>: Immunohistochemical staining of human breast shows strong cytoplasmic and membranous positivity in glandular cells.

Anti-C16ORF73 antibody produced in rabbit - SAB2105981 from Sigma-Aldrich

Prices	$347.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-C16ORF73: <B>Cat. No. SAB2105981</B>: C16orf73 in Fetal liver cell lysates with C16orf73 antibody at 1.0 μg/mL.

MEIOB Antibody - C-terminal region (ARP55533_P050) - ARP55533_P050 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

C16orf73 antibody - middle region (ARP55534_P050) - ARP55534_P050 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

C16orf73 antibody, Internal - GTX45259 from GeneTex

Prices	$319.00
Sizes	50 μg
Host	Rabbit
Clonality	Polyclonal

Anti-C16orf73 antibody, Internal used in Western blot. GTX45259

C16orf73 antibody - 70R-4561 from Fitzgerald

Prices	$345.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

C16orf73 antibody - H00254528-B01P from Acris Antibodies

Prices	$1,530.00
Sizes	500 µg
Host	Mouse
Clonality	Polyclonal

C16orf73 Antibody - GWB-MT892A from Genway Biotech

Prices	$368.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-C16ORF73 (aa 193-285) polyclonal antibody - DPABH-03033 from Creative Diagnostics

Host	Rabbit
Clonality	Polyclonal

Anti-C16ORF73 (aa 19-99) polyclonal antibody - DPABH-03035 from Creative Diagnostics

Host	Rabbit
Clonality	Polyclonal

Anti-C16ORF73 (aa 264-313) polyclonal antibody - DPABH-12861 from Creative Diagnostics

Host	Rabbit
Clonality	Polyclonal

C16orf73-antibody-middle-region-AI13811 - AI13811 from Abgent, a WuXi AppTec company

Prices	$293.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

WB Suggested Anti-C16orf73 Antibody Titration: 0.2-1 ug/ml Positive Control: Human Liver

MEIOB-Antibody-C-terminal-region-AI13810 - AI13810 from Abgent, a WuXi AppTec company

Prices	$293.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Host: Rabbit Target Name: MEIOB Sample Tissue: Uterus Tumor lysates Antibody Dilution: 1.0ug/ml

C16orf73, Polyclonal Antibody - MBS5303362 from MyBioSource

Prices	$455.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

C16orf73 antibody - TA329791 from Acris Antibodies

Prices	$325.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

C16orf73 antibody - TA329792 from Acris Antibodies

Prices	$325.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-C16orf73 Antibody (C-Terminus, Biotin) - LS-C460306 from LifeSpan Bioscience

Prices	$385.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

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