GDF9

Gene Symbol GDF9
Entrez Gene 2661
Alt Symbol -
Species Human
Gene Type protein-coding
Description growth differentiation factor 9
Other Description GDF-9|growth/differentiation factor 9
Swissprots Q4VAW5 O60383
Accessions AAC08450 EAW62309 O60383 AA604716 AK301962 BAG63375 AK315973 BAH14344 BC096228 AAH96228 BC096229 AAH96229 BC096230 AAH96230 BC096231 AAH96231 BX117145 CA488820 DB040027 DB320693 HY015857 HY042819 HY045713 HY211060 XM_005271957 XP_005272014 XM_006714585 XP_006714648 XM_011543308 XP_011541610 XM_011543309 XP_011541611 XM_011543310 XP_011541612 XM_011543311 XP_011541613 NM_001288824 NP_001275753 NM_001288825 NP_001275754 NM_001288826 NP_001275755 NM_001288827 NP_001275756 NM_001288828 NP_001275757 NM_005260 NP_005251
Function Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells. {ECO:0000269|PubMed:12050262, ECO:0000269|PubMed:19366876, ECO:0000269|PubMed:20660033, ECO:0000269|PubMed:21632818, ECO:0000269|PubMed:21829661}.
Subcellular Location Secreted {ECO:0000250}.
Tissue Specificity Expressed in ovarian granulosa cells. Present in oocytes of primary follicles (at protein level). {ECO:0000269|PubMed:10443672, ECO:0000269|PubMed:12050262}.
Top Pathways Ovarian steroidogenesis

GDF-9 (C-18) - sc-12244 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

GDF-9 (C-20) - sc-7407 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GDF-9 (C-20): sc-7407. Western blot analysis of GDF-9 expression in mouse brain tissue extract.

GDF-9 (H-124) - sc-366853 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-GDF 9 antibody - ab93892 from Abcam

Prices $380.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab93892 staining GDF 9 in Rat ovary tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with paraformaldehyde and blocked with 1.5% serum for 1 hour at 24°C; antigen retrieval was enzymatic. Samples were incubated with primary antibody (1μg/ml) for 12 hours at 4°C. A Biotin-conjugated Goat anti-rabbit IgG polyclonal (1/200) was used as the secondary antibody.See Abreview

Anti-GDF 9 antibody - ab38544 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-GDF 9 antibody (ab38544) at 1/100 dilution + HL60 cell lysate

Anti-GDF 9 antibody - ab193443 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GDF 9 antibody - ab169286 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-GDF 9 antibody (ab169286) at 1 µg/mlLane 1 : GDF 9 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilutiondeveloped using the ECL technique

Anti-GDF9 / GDF-9 Antibody - LS-C24058 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-GDF9 / GDF-9 Antibody (aa87-117, Biotin) - LS-C235610 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GDF9 / GDF-9 Antibody (aa87-117, APC) - LS-C235608 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GDF9 / GDF-9 Antibody (aa87-117, AP) - LS-C235607 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GDF9 / GDF-9 Antibody (aa87-117, FITC) - LS-C235611 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GDF9 / GDF-9 Antibody (N-Terminus, APC) - LS-C244568 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GDF9 / GDF-9 Antibody (aa87-117, PE) - LS-C235614 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GDF9 / GDF-9 Antibody (N-Terminus, Biotin) - LS-C244569 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GDF9 / GDF-9 Antibody (N-Terminus, AP) - LS-C244570 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GDF9 / GDF-9 Antibody (N-Terminus, FITC) - LS-C244571 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GDF9 / GDF-9 Antibody (N-Terminus, Azide-free, HRP) - LS-C247615 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GDF9 / GDF-9 Antibody (N-Terminus, PE) - LS-C244573 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GDF9 / GDF-9 Antibody (aa87-117, Azide-free, HRP) - LS-C249054 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GDF9 / GDF-9 Antibody - LS-C147177 from LifeSpan Bioscience

Prices $410.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of GDF9 antibody LS-C147177.

Anti-GDF9 / GDF-9 Antibody (aa273-322) - LS-C291694 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GDF9 / GDF-9 Antibody (aa320-454, Biotin) - LS-C298809 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GDF9 / GDF-9 Antibody (aa320-454, FITC) - LS-C305188 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GDF9 / GDF-9 Antibody - LS-C307669 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
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