GDF9

Gene Symbol	GDF9
Entrez Gene	2661
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	growth differentiation factor 9
Other Description	GDF-9|growth/differentiation factor 9
Swissprots	Q4VAW5 O60383
Accessions	AAC08450 EAW62309 O60383 AA604716 AK301962 BAG63375 AK315973 BAH14344 BC096228 AAH96228 BC096229 AAH96229 BC096230 AAH96230 BC096231 AAH96231 BX117145 CA488820 DB040027 DB320693 HY015857 HY042819 HY045713 HY211060 XM_005271957 XP_005272014 XM_006714585 XP_006714648 XM_011543308 XP_011541610 XM_011543309 XP_011541611 XM_011543310 XP_011541612 XM_011543311 XP_011541613 NM_001288824 NP_001275753 NM_001288825 NP_001275754 NM_001288826 NP_001275755 NM_001288827 NP_001275756 NM_001288828 NP_001275757 NM_005260 NP_005251
Function	Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells. {ECO:0000269|PubMed:12050262, ECO:0000269|PubMed:19366876, ECO:0000269|PubMed:20660033, ECO:0000269|PubMed:21632818, ECO:0000269|PubMed:21829661}.
Subcellular Location	Secreted {ECO:0000250}.
Tissue Specificity	Expressed in ovarian granulosa cells. Present in oocytes of primary follicles (at protein level). {ECO:0000269|PubMed:10443672, ECO:0000269|PubMed:12050262}.
Top Pathways	Ovarian steroidogenesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-GDF9-cDNA-Clone - DC09062 from Abgent, a WuXi AppTec company Prices $612.90 Sizes 10 µg Species Human Accession BC096228

GDF9 - MBS1278436 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC096228

Human GDF9 ORF Clone(NM_005260.3) - CDCL164509 from Creative Biomart Species Human Accession NM_005260.3

Human GDF-9 Gene cDNA clone plasmid - HG10938-M from Sino Biological Species Human

Human GDF-9 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10938-M-F from Sino Biological Species Human

Human GDF-9 Gene ORF cDNA clone expression plasmid - HG10938-M-N from Sino Biological Species Human

Human GDF-9 ORF clone(NM_005260.3) - CDCL184388 from Creative biogene Species Human

Human GDF9 ORF Clone (BC096228) - CDCS412166 from Creative biogene Species Human Accession O60383

Human Growth Differentiation Factor 9 Gene - orb91392 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human GDF-9 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10938-ACG from Sino Biological Species Human

Human GDF-9 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10938-CF from Sino Biological Species Human

Human GDF-9 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10938-NM from Sino Biological Species Human

Human GDF-9 Gene ORF cDNA clone expression plasmid, N-His tag - HG10938-NH from Sino Biological Species Human

Human GDF-9 Gene ORF cDNA clone expression plasmid - HG10938-UT from Sino Biological Species Human

Human GDF-9 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10938-CM from Sino Biological Species Human

Human GDF-9 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10938-ACR from Sino Biological Species Human

Human GDF-9 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10938-NF from Sino Biological Species Human

Human GDF-9 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10938-NY from Sino Biological Species Human

Human GDF-9 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10938-CY from Sino Biological Species Human

Human GDF-9 Gene ORF cDNA clone expression plasmid, C-His tag - HG10938-CH from Sino Biological Species Human

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