RTCB

Gene Symbol RTCB
Entrez Gene 51493
Alt Symbol C22orf28, DJ149A16.6, FAAP, HSPC117
Species Human
Gene Type protein-coding
Description RNA 2',3'-cyclic phosphate and 5'-OH ligase
Other Description ankyrin repeat domain 54|focal adhesion-associated protein|tRNA-splicing ligase RtcB homolog
Swissprots Q9BWL4 Q9P037 B2R6A8 Q9P0J3 Q9Y3I0 Q9NTH1 Q6IAI0
Accessions EAW60021 Q9Y3I0 AF155658 AAF67477 AF161466 AAF29081 AK297826 BAG60162 AK297908 BAG60227 AK301945 BAG63363 AK312503 BAG35405 AL050255 CAB43357 AL137272 CAB70670 BC000151 AAH00151 BC002970 AAH02970 BC010308 AAH10308 BC016707 AAH16707 BU615556 CR456450 CAG30336 CR457175 CAG33456 DC396330 DQ890931 ABM81857 DQ894092 ABM85018 NM_014306 NP_055121
Function Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'- phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs. {ECO:0000269|PubMed:21311021, ECO:0000269|PubMed:24870230}.
Subcellular Location Nucleus {ECO:0000269|PubMed:24608264}. Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03144, ECO:0000269|PubMed:24608264}. Note=Enters into the nucleus in case of active transcription while it accumulates in cytosol when transcription level is low. {ECO:0000269|PubMed:24608264}.

HSPC117 CRISPR/Cas9 KO Plasmid (h) - sc-407525 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSPC117 HDR Plasmid (h) - sc-407525-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSPC117 Double Nickase Plasmid (h) - sc-407525-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSPC117 Double Nickase Plasmid (h2) - sc-407525-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSPC117 CRISPR Activation Plasmid (h) - sc-407525-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSPC117 CRISPR Activation Plasmid (h2) - sc-407525-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSPC117 Lentiviral Activation Particles (h) - sc-407525-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSPC117 Lentiviral Activation Particles (h2) - sc-407525-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSPC117 siRNA (h) - sc-75311 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HSPC117 shRNA Plasmid (h) - sc-75311-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HSPC117 shRNA (h) Lentiviral Particles - sc-75311-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU009301 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4791 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4791 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03684 from Sigma-Aldrich

Category miRNA

RTCB siRNA (Human) - CRH9791 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RTCB - MBS8233874 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human RTCB siRNA - orb270293 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RTCB shRNA Plasmid (Human) - CHH9791 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

C22ORF28 miRNA 3'UTR clone - MiUTR3H-13070 from Creative biogene

Species Reactivities Human
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