RTCB

Gene Symbol RTCB
Entrez Gene 51493
Alt Symbol C22orf28, DJ149A16.6, FAAP, HSPC117
Species Human
Gene Type protein-coding
Description RNA 2',3'-cyclic phosphate and 5'-OH ligase
Other Description ankyrin repeat domain 54|focal adhesion-associated protein|tRNA-splicing ligase RtcB homolog
Swissprots Q9BWL4 Q9P037 B2R6A8 Q9P0J3 Q9Y3I0 Q9NTH1 Q6IAI0
Accessions EAW60021 Q9Y3I0 AF155658 AAF67477 AF161466 AAF29081 AK297826 BAG60162 AK297908 BAG60227 AK301945 BAG63363 AK312503 BAG35405 AL050255 CAB43357 AL137272 CAB70670 BC000151 AAH00151 BC002970 AAH02970 BC010308 AAH10308 BC016707 AAH16707 BU615556 CR456450 CAG30336 CR457175 CAG33456 DC396330 DQ890931 ABM81857 DQ894092 ABM85018 NM_014306 NP_055121
Function Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'- phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs. {ECO:0000269|PubMed:21311021, ECO:0000269|PubMed:24870230}.
Subcellular Location Nucleus {ECO:0000269|PubMed:24608264}. Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03144, ECO:0000269|PubMed:24608264}. Note=Enters into the nucleus in case of active transcription while it accumulates in cytosol when transcription level is low. {ECO:0000269|PubMed:24608264}.

HSPC117/FAAP (N-14) - sc-86491 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
HSPC117/FAAP (N-14): sc-86491. Western blot analysis of HSPC117 expression in non-transfected: sc-117752 (A) and human HSPC117 transfected: sc-369180 (B) 293T whole cell lysates.

HSPC117/FAAP (S-15) - sc-86492 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
HSPC117/FAAP (S-15): sc-86492. Western blot analysis of HSPC117 expression in non-transfected: sc-117752 (A) and human HSPC117 transfected: sc-369180 (B) 293T whole cell lysates.

HSPC117 (C-3) - sc-393966 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HSPC117 (C-3): sc-393966. Western blot analysis of HSPC117 expression in Jurkat (A), HeLa (B), MCF7 (C), Hep G2 (D) and A-431 (E) whole cell lysates.

HSPC117 (H-300) - sc-292908 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
HSPC117 (H-300): sc-292908. Western blot analysis of HSPC117 expression in Jurkat (A), HeLa (B) and Hep G2 (C) whole cell lysates.

Anti-C22orf28 antibody - ab118284 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-C22orf28 antibody (ab118284) at 0.05 µg/ml + Jurkat lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-C22orf28 antibody - ab118290 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Staining of Human Testis by ab118290 (5μg/mL) in paraffin embedded tissue following stemaed antigen retieval with citrat buffer pH6, AP-Staining this shows nuclear and vicinity staining in spermatogonia.

Anti-RTCB / C22orf28 Antibody (aa125-138) - LS-C139807 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-RTCB / C22orf28 Antibody (aa201-214) IHC-plus™ - LS-B10474 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Human, Testis: Formalin-Fixed Paraffin-Embedded (FFPE)

Anti-RTCB / C22orf28 Antibody (FITC) - LS-C318002 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RTCB / C22orf28 Antibody (HRP) - LS-C318003 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RTCB / C22orf28 Antibody - LS-C318005 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RTCB / C22orf28 Antibody (Biotin) - LS-C318999 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RTCB / C22orf28 Antibody (aa107-156) - LS-C107762 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
C22orf28 antibody LS-C107762 Western blot of HepG2 cell lysate.

Anti-RTCB / C22orf28 Antibody (aa359-408) - LS-C107763 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
C22orf28 antibody LS-C107763 Western blot of MCF7 cell lysate.

FAAP Antibody - NBP1-56855 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: FAAP Antibody [NBP1-56855] - Reccomended Titration: 0.2 - 1 ug/ml ELISA Titer: 1:62500 Positive Control: HepG2 cell lysate

FAAP Antibody - NBP1-83175 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: FAAP Antibody [NBP1-83175] - Analysis in human cell line U-251 MG.

FAAP Antibody - NBP1-56856 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

C22orf28 Polyclonal Antibody - bs-9985R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-C22orf28 antibody produced in goat - SAB2501884 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-C22orf28: <B>Cat. No. SAB2501884</B>: (0.3 μg/mL) staining of HeLa lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-C22ORF28, (N-terminal) antibody produced in rabbit - SAB2104959 from Sigma-Aldrich

Prices $347.50
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-C22ORF28, antibody produced in rabbit: <B>Cat. No. SAB2104959</B>: Immunoblotting analysis of C22orf28 in HepG2 cell lysate with C22orf28 anitbody at 1 μg/mL.

Anti-C22orf28 antibody produced in goat - SAB2501885 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-C22orf28: <B>Cat. No. SAB2501885</B>: (0.05 μg/mL) staining of Jurkat lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-C22ORF28 antibody produced in rabbit - SAB2104960 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-C22ORF28, antibody produced in rabbit: <B>Cat. No. SAB2104960</B>: Immunoblotting analysis of C22orf28 in MCF7 cell lysate with C22orf28 anitbody at 1 μg/mL.

C22orf28 antibody - N-terminal region (ARP56745_P050) - ARP56745_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C22orf28 antibody - middle region (ARP56746_P050) - ARP56746_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HSPC117-aa125-138-Antibody-internal-region - AF3555a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF3555a (0.05 µg/ml) staining of Jurkat lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Search more