| Gene Symbol |
CHERP
|
| Entrez Gene |
10523
|
| Alt Symbol |
DAN16, SCAF6, SRA1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
calcium homeostasis endoplasmic reticulum protein
|
| Other Description |
ERPROT 213-21|ERPROT213-21|SR-related CTD associated factor 6|SR-related CTD-associated factor 6|protein with polyglutamine repeat
|
| Swissprots |
Q8IWX8 Q99492 Q4G0Y5 Q8WU30 O00302
|
| Accessions |
EAW84549 Q8IWX8 AA782418 AB209730 BAD92967 AF536542 AAN77183 AK296883 BAG59444 AK298408 BAG60636 BC001552 BC021294 AAH21294 BC035039 CN336425 U94836 AAB53327 Y08265 CAA69591 NM_006387 NP_006378
|
| Function |
Involved in calcium homeostasis, growth and proliferation. {ECO:0000269|PubMed:10794731, ECO:0000269|PubMed:12656674}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:10794731, ECO:0000269|PubMed:12656674, ECO:0000269|PubMed:8010949}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:10794731, ECO:0000269|PubMed:12656674, ECO:0000269|PubMed:8010949}. Endoplasmic reticulum {ECO:0000269|PubMed:10794731, ECO:0000269|PubMed:12656674, ECO:0000269|PubMed:8010949}. Note=Distributed throughout the cytoplasm and also localizes to the perinuclear region of both human erythroleukemia (HEL) cells and Jurkat cells. Colocalizes with ITPR1. {ECO:0000269|PubMed:10794731, ECO:0000269|PubMed:12656674, ECO:0000269|PubMed:8010949}.
|
| Tissue Specificity |
Expressed in brain, placenta, lung, liver, kidney, pancreas, cardiac and skeletal muscle, and in cultured HEL and Dami cells. {ECO:0000269|PubMed:10794731}.
|
| Top Pathways |
Spliceosome
|