Gene Symbol | CHERP |
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Entrez Gene | 10523 |
Alt Symbol | DAN16, SCAF6, SRA1 |
Species | Human |
Gene Type | protein-coding |
Description | calcium homeostasis endoplasmic reticulum protein |
Other Description | ERPROT 213-21|ERPROT213-21|SR-related CTD associated factor 6|SR-related CTD-associated factor 6|protein with polyglutamine repeat |
Swissprots | Q8IWX8 Q99492 Q4G0Y5 Q8WU30 O00302 |
Accessions | EAW84549 Q8IWX8 AA782418 AB209730 BAD92967 AF536542 AAN77183 AK296883 BAG59444 AK298408 BAG60636 BC001552 BC021294 AAH21294 BC035039 CN336425 U94836 AAB53327 Y08265 CAA69591 NM_006387 NP_006378 |
Function | Involved in calcium homeostasis, growth and proliferation. {ECO:0000269|PubMed:10794731, ECO:0000269|PubMed:12656674}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:10794731, ECO:0000269|PubMed:12656674, ECO:0000269|PubMed:8010949}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:10794731, ECO:0000269|PubMed:12656674, ECO:0000269|PubMed:8010949}. Endoplasmic reticulum {ECO:0000269|PubMed:10794731, ECO:0000269|PubMed:12656674, ECO:0000269|PubMed:8010949}. Note=Distributed throughout the cytoplasm and also localizes to the perinuclear region of both human erythroleukemia (HEL) cells and Jurkat cells. Colocalizes with ITPR1. {ECO:0000269|PubMed:10794731, ECO:0000269|PubMed:12656674, ECO:0000269|PubMed:8010949}. |
Tissue Specificity | Expressed in brain, placenta, lung, liver, kidney, pancreas, cardiac and skeletal muscle, and in cultured HEL and Dami cells. {ECO:0000269|PubMed:10794731}. |
Top Pathways | Spliceosome |
CHERP (E-14) - sc-167461 from Santa Cruz Biotechnology
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CHERP (SS5) - sc-100650 from Santa Cruz Biotechnology
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Anti-CHERP antibody - ab15951 from Abcam
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Anti-CHERP antibody - ab192400 from Abcam
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Anti-CHERP antibody - ab84113 from Abcam
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Anti-CHERP antibody - C-terminal - ab173156 from Abcam
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Anti-CHERP Antibody (aa795-883) - LS-C306935 from LifeSpan Bioscience
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Anti-CHERP Antibody - LS-C306934 from LifeSpan Bioscience
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Anti-CHERP Antibody (aa876-903) - LS-C320349 from LifeSpan Bioscience
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Anti-CHERP Antibody - LS-C340957 from LifeSpan Bioscience
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Anti-CHERP Antibody (aa827-915) - LS-C125233 from LifeSpan Bioscience
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Anti-CHERP Antibody (aa795-884, clone 10B2216, Azide-free) - LS-C183499 from LifeSpan Bioscience
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Anti-CHERP Antibody (C-Terminus) - LS-C101864 from LifeSpan Bioscience
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Anti-CHERP Antibody (aa876-903, AP) - LS-C213288 from LifeSpan Bioscience
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Anti-CHERP Antibody (aa683-732) - LS-C110548 from LifeSpan Bioscience
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Anti-CHERP Antibody (aa876-903, APC) - LS-C213289 from LifeSpan Bioscience
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Anti-CHERP Antibody (aa876-903, Biotin) - LS-C213290 from LifeSpan Bioscience
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Anti-CHERP Antibody (aa876-903) - LS-C159344 from LifeSpan Bioscience
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Anti-CHERP Antibody (aa876-903, FITC) - LS-C213291 from LifeSpan Bioscience
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Anti-CHERP Antibody (aa876-903, Azide-free, HRP) - LS-C213292 from LifeSpan Bioscience
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Anti-CHERP Antibody (aa876-903, PE) - LS-C213293 from LifeSpan Bioscience
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CHERP Antibody - NBP1-80457 from Novus Biologicals
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CHERP Antibody - NBP1-80456 from Novus Biologicals
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CHERP Antibody - NBP2-13837 from Novus Biologicals
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CHERP Antibody (1A5) - H00010523-M02 from Novus Biologicals
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