AGRN

Gene Symbol AGRN
Entrez Gene 375790
Alt Symbol CMSPPD
Species Human
Gene Type protein-coding
Description agrin
Other Description agrin proteoglycan
Swissprots Q96IC1 Q7KYS8 Q9BTD4 O00468 Q5SVA1 Q5SVA2 Q8N4J5 Q60FE1
Accessions EAW56293 O00468 AB191264 BAD52440 AF016903 AAC39776 AJ309206 CAC42508 AK021586 BAG51039 AK125197 AK128761 AW119098 AW204172 BC004220 AAH04220 BC007649 AAH07649 BC034009 AAH34009 BC063620 AAH63620 BC084578 AAH84578 BE383214 BF569502 BF740118 BQ892267 CK000983 CN314674 CN314678 HG491578 S44195 AAB23327 U84406 AAB52917 XM_005244749 XP_005244806 XM_006710635 XP_006710698 XM_011541429 XP_011539731 XM_011541430 XP_011539732 XM_011541431 XP_011539733 XR_946650 NM_001305275 NP_001292204 NM_198576 NP_940978
Function Agrin N-terminal 110 kDa subunit: is involved in regulation of neurite outgrowth probably due to the presence of the glycosaminoglcan (GAG) side chains of heparan and chondroitin sulfate attached to the Ser/Thr- and Gly/Ser-rich regions. Also involved in modulation of growth factor signaling (By similarity). {ECO:0000250}.
Subcellular Location Isoform 1: Secreted, extracellular space, extracellular matrix. Note=Synaptic basal lamina at the neuromuscular junction. {ECO:0000250}.
Tissue Specificity Expressed in basement membranes of lung and kidney. Muscle- and neuron-specific isoforms are found. Isoforms (y+) with the 4 AA insert and (z+8) isoforms with the 8 AA insert are all neuron-specific. Isoforms (z+11) are found in both neuronal and non-neuronal tissues. {ECO:0000269|PubMed:16487930, ECO:0000269|PubMed:20551380, ECO:0000269|PubMed:9652404}.
Top Pathways ECM-receptor interaction

Agrin (D-2) - sc-374117 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Agrin (D-2): sc-374117. Western blot analysis of Agrin expression in SK-N-SH (A) and LADMAC (B) whole cell lysates.

Agrin (H-300) - sc-25528 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Agrin siRNA (m): sc-29653. Western blot analysis of Agrin expression in non-transfected control (A) and Agrin siRNA transfected (B) LADMAC cells. Blot probed with Agrin (H-300): sc-25528. α-actinin (H-2): sc-17829 used as specificity and loading control.

Agrin (K-17) - sc-6166 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Agrin (K-17): sc-6166. Immunofluorescence staining of methanol-fixed SK-N-SH cells showing membrane localization.

Agrin (R-20) - sc-6040 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Agrin (R-20): sc-6040. Western blot analysis of Agrin expression in EOC 20 whole cell lysate.

Anti-Agrin antibody - ab85174 from Abcam

Prices $387.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab85174, at 1/100 dilution, staining Agrin in formalin-fixed, paraffin-embedded human skeletal muscle by Immunohistochemistry.

Anti-AGRN / Agrin Antibody (aa1206-1475) - LS-C314745 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant AGRN / Agrin.

Anti-AGRN / Agrin Antibody (aa1856-2045) - LS-C314746 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant AGRN / Agrin.

Anti-AGRN / Agrin Antibody (N-Terminus) - LS-C137122 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-AGRN / Agrin Antibody (C-Terminus) - LS-C11825 from LifeSpan Bioscience

Prices $530.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal

Anti-AGRN / Agrin Antibody - LS-C45609 from LifeSpan Bioscience

Prices $875.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal

Anti-AGRN / Agrin Antibody (C-Terminus, clone AGR 131) - LS-C63141 from LifeSpan Bioscience

Prices $310.00, $465.00
Sizes 50 µg, 200 µg
Host Mouse
Clonality Monoclonal

Anti-AGRN / Agrin Antibody (C-Terminus, clone Agr-33) - LS-C63140 from LifeSpan Bioscience

Prices $305.00, $450.00
Sizes 50 µg, 200 µg
Host Mouse
Clonality Monoclonal
Clone Agr-33

Anti-AGRN / Agrin Antibody (C-Terminus) - LS-C11829 from LifeSpan Bioscience

Prices $375.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-AGRN / Agrin Antibody (C-Terminus) - LS-C63820 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-AGRN / Agrin Antibody (C-Terminus, clone Agr247) - LS-C63142 from LifeSpan Bioscience

Prices $295.00, $465.00
Sizes 50 µg, 200 µg
Host Mouse
Clonality Monoclonal
Clone Agr247

Anti-AGRN / Agrin Antibody (C-Terminus) - LS-C63821 from LifeSpan Bioscience

Prices $530.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-AGRN / Agrin Antibody - LS-C342124 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Agrin Antibody - NBP1-90209 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: Agrin Antibody [NBP1-90209] - Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.

Agrin Polyclonal Antibody - bs-1176R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Agrin Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-1176R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Agrin Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-1176R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Agrin Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-1176R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Agrin Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-1176R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Agrin Polyclonal Antibody, Cy3 Conjugated - bs-1176R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Agrin Polyclonal Antibody, Cy5 Conjugated - bs-1176R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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