AGRN

Gene Symbol AGRN
Entrez Gene 375790
Alt Symbol CMSPPD
Species Human
Gene Type protein-coding
Description agrin
Other Description agrin proteoglycan
Swissprots Q96IC1 Q7KYS8 Q9BTD4 O00468 Q5SVA1 Q5SVA2 Q8N4J5 Q60FE1
Accessions EAW56293 O00468 AB191264 BAD52440 AF016903 AAC39776 AJ309206 CAC42508 AK021586 BAG51039 AK125197 AK128761 AW119098 AW204172 BC004220 AAH04220 BC007649 AAH07649 BC034009 AAH34009 BC063620 AAH63620 BC084578 AAH84578 BE383214 BF569502 BF740118 BQ892267 CK000983 CN314674 CN314678 HG491578 S44195 AAB23327 U84406 AAB52917 XM_005244749 XP_005244806 XM_006710635 XP_006710698 XM_011541429 XP_011539731 XM_011541430 XP_011539732 XM_011541431 XP_011539733 XR_946650 NM_001305275 NP_001292204 NM_198576 NP_940978
Function Agrin N-terminal 110 kDa subunit: is involved in regulation of neurite outgrowth probably due to the presence of the glycosaminoglcan (GAG) side chains of heparan and chondroitin sulfate attached to the Ser/Thr- and Gly/Ser-rich regions. Also involved in modulation of growth factor signaling (By similarity). {ECO:0000250}.
Subcellular Location Isoform 1: Secreted, extracellular space, extracellular matrix. Note=Synaptic basal lamina at the neuromuscular junction. {ECO:0000250}.
Tissue Specificity Expressed in basement membranes of lung and kidney. Muscle- and neuron-specific isoforms are found. Isoforms (y+) with the 4 AA insert and (z+8) isoforms with the 8 AA insert are all neuron-specific. Isoforms (z+11) are found in both neuronal and non-neuronal tissues. {ECO:0000269|PubMed:16487930, ECO:0000269|PubMed:20551380, ECO:0000269|PubMed:9652404}.
Top Pathways ECM-receptor interaction

Agrin CRISPR/Cas9 KO Plasmid (h) - sc-401256 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Agrin HDR Plasmid (h) - sc-401256-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Agrin Double Nickase Plasmid (h) - sc-401256-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Agrin Double Nickase Plasmid (h2) - sc-401256-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Agrin CRISPR Activation Plasmid (h) - sc-401256-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Agrin CRISPR Activation Plasmid (h2) - sc-401256-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Agrin Lentiviral Activation Particles (h) - sc-401256-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Agrin Lentiviral Activation Particles (h2) - sc-401256-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Agrin siRNA (h) - sc-29652 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Agrin shRNA Plasmid (h) - sc-29652-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Agrin shRNA (h) Lentiviral Particles - sc-29652-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Agrin RNAi - H00375790-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU139461 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2958 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2958 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

AGRN siRNA (Human) - CRJ7686 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AGRN - MBS8201379 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human AGRN (NM_198576.3) - SHH233454 from Creative biogene

Category siRNA
Species Reactivities Human

Human AGRN siRNA - orb278187 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AGRN shRNA Plasmid (Human) - CHJ7686 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

AGRN miRNA 3'UTR clone - MiUTR3H-00087 from Creative biogene

Species Reactivities Human
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