AGRN

Gene Symbol	AGRN
Entrez Gene	375790
Alt Symbol	CMSPPD
Species	Human
Gene Type	protein-coding
Description	agrin
Other Description	agrin proteoglycan
Swissprots	Q96IC1 Q7KYS8 Q9BTD4 O00468 Q5SVA1 Q5SVA2 Q8N4J5 Q60FE1
Accessions	EAW56293 O00468 AB191264 BAD52440 AF016903 AAC39776 AJ309206 CAC42508 AK021586 BAG51039 AK125197 AK128761 AW119098 AW204172 BC004220 AAH04220 BC007649 AAH07649 BC034009 AAH34009 BC063620 AAH63620 BC084578 AAH84578 BE383214 BF569502 BF740118 BQ892267 CK000983 CN314674 CN314678 HG491578 S44195 AAB23327 U84406 AAB52917 XM_005244749 XP_005244806 XM_006710635 XP_006710698 XM_011541429 XP_011539731 XM_011541430 XP_011539732 XM_011541431 XP_011539733 XR_946650 NM_001305275 NP_001292204 NM_198576 NP_940978
Function	Agrin N-terminal 110 kDa subunit: is involved in regulation of neurite outgrowth probably due to the presence of the glycosaminoglcan (GAG) side chains of heparan and chondroitin sulfate attached to the Ser/Thr- and Gly/Ser-rich regions. Also involved in modulation of growth factor signaling (By similarity). {ECO:0000250}.
Subcellular Location	Isoform 1: Secreted, extracellular space, extracellular matrix. Note=Synaptic basal lamina at the neuromuscular junction. {ECO:0000250}.
Tissue Specificity	Expressed in basement membranes of lung and kidney. Muscle- and neuron-specific isoforms are found. Isoforms (y+) with the 4 AA insert and (z+8) isoforms with the 8 AA insert are all neuron-specific. Isoforms (z+11) are found in both neuronal and non-neuronal tissues. {ECO:0000269|PubMed:16487930, ECO:0000269|PubMed:20551380, ECO:0000269|PubMed:9652404}.
Top Pathways	ECM-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Human Agrin protein fragment - ab91861 from Abcam Category Protein Prices $119.00 Sizes 20 µg Source E. coli Species Human

Recombinant Human Agrin, CF - 6624-AG-050 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Ala1260-Pro2045, with an N-terminal 6-His tag

Agrin Blocking Peptide - abx064292 from Abbexa Category Peptide Species Human, Mouse, Rat

Recombinant Human AGRN, His-tagged - AGRN-26658TH from Creative Biomart Category Protein Source E. coli

Recombinant Human Agrin, His-tagged - AGRN-131H from Creative Biomart Category Protein Source Sf9 insect cells.

Recombinant Human AGRN, His-tagged - AGRN-132H from Creative Biomart Category Protein Source CHO Cells Species Human

Recombinant Human AGRN - AGRN-138H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human AGRN, His-tagged - AGRN-875H from Creative Biomart Category Protein Source CHO Cells Species Human

Recombinant Agrin (AGRN) - RPB303Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Agrin (AGRN) - RPB303Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Agrin (AGRN) - RPB303Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Agrin Blocking Peptide - CBP3098 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

Recombinant Agrin (AGRN) - RPB303Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Agrin(AGRN) ,partial - CSB-YP001461HU CSB-EP001461HU CSB-BP001461HU CSB-MP001461HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Agrin Protein, CF - 6624-AG from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Chinese Hamster Ovary cell line, CHO-derived Ala1260-Pro2045, with an N-terminal 6-His tag Species Human

Agrin - MBS2029287 from MyBioSource Category Protein Prices $185.00, $300.00, $440.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

Agrobacterium tumefaciens T-DNA border endonuclease virD2 - MBS1100013 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Agrin Protein (Recombinant) - abx166410 from Abbexa Category Protein Source Human Species Human

Recombinant Human Agrin Protein, N-terminal, CF - 8909-AG from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Chinese Hamster Ovary cell line, CHO-derived Thr30-Arg1102, with a C-terminal 6-His tag Species Human

Recombinant Agrin (AGRN) - RPB303Hu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Human AGRN protein, His/T7-tagged - AGRN-12H from Creative Biomart Category Protein Source E. coli Species Human

Agrin Recombinant Protein Antigen - NBP1-90209PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Recombinant Agrin (AGRN) - RPU50486 from Biomatik Category Protein Prices $166.00, $288.00, $440.00, $550.40 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

Recombinant Agrin (AGRN) - RPU50487 from Biomatik Category Protein Prices $166.00, $288.00, $440.00, $550.40 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

AGRN Recombinant Protein (OPCD00267) - OPCD00267 from Aviva Systems Biology Category Protein Source E.coli Species Human

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