E2F1

Gene Symbol	E2F1
Entrez Gene	1869
Alt Symbol	E2F-1, RBAP1, RBBP3, RBP3
Species	Human
Gene Type	protein-coding
Description	E2F transcription factor 1
Other Description	PBR3|PRB-binding protein E2F-1|RBAP-1|RBBP-3|retinoblastoma-associated protein 1|retinoblastoma-binding protein 3|transcription factor E2F1
Swissprots	Q13143 Q92768 Q01094
Accessions	AAC50719 AAD14150 AAM47604 CAM91159 CAN37617 CAY56011 CBX53852 EAW76299 EAW76300 Q01094 AF086380 BC005098 AAH05098 BC050369 AAH50369 BC058902 AAH58902 M96577 AAA35782 S49592 AAB24289 NM_005225 NP_005216
Function	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters (PubMed:20176812). {ECO:0000250|UniProtKB:Q61501, ECO:0000269|PubMed:10675335, ECO:0000269|PubMed:12717439, ECO:0000269|PubMed:17704056, ECO:0000269|PubMed:20176812, ECO:0000269|PubMed:8170954}.
Subcellular Location	Nucleus.
Top Pathways	MicroRNAs in cancer, Cell cycle, HTLV-I infection, Prostate cancer, Glioma

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human Phospho-E2F1 (Thr433) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1129 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.156-10 g/ml

Mouse/Human E2F1 ELISA Kit (Cell-Based ELISA) - LS-F1950 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.156-10 g/ml

Human E2F1 ELISA Kit (Sandwich ELISA) - LS-F9163 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.054 g/ml Range 0.156-10 g/ml

Rabbit anti-E2F1 Antibody, Affinity Purified - PLA0139 from Sigma-Aldrich Prices $323.50 Sizes 100 µl

Human E2F1 ELISA Kit - abx151365 from Abbexa Category ELISA Kit Sensitivity 0.054 g/ml Range 0.156 g/ml - 10 g/ml

E2F Transcription Factor 1 (E2F1), Human, ELISA Kit - SEJ181Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.054g/mL Range 0.156-10ng/mL

E2F transcription factor 1, Human, ELISA Kit - E01E0365 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

E2F Transcription Factor 2 (E2F2), Human, ELISA Kit - SEJ182Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.068ng/mL Range 0.156-10ng/mL

E2F Transcription Factor 3 (E2F3), Human, ELISA Kit - SEJ183Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.072ng/mL Range 0.156-10ng/mL

Transcription factor E2F1 (E2F1), Human, ELISA Kit - E01T0610 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Transcription factor E2F1 (E2F1), ELISA Kit - MBS7227470 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor E2F1 (E2F1), ELISA Kit - MBS7213253 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor E2F1 (E2F1), ELISA Kit - MBS7204294 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor E2F1 (E2F1), ELISA Kit - MBS7250664 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E2F1 Colorimetric Cell-Based ELISA Kit - CB5215 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

E2F1 (Phospho-Thr433) Colorimetric Cell-Based ELISA Kit - CBP1113 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Human RBP3(Retinol Binding Protein 3, Interstitial) ELISA Kit - E-EL-H1585 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

Human RBP3 (Retinol Binding Protein 3, Interstitial) CLIA Kit - E-CL-H1019 from Elabscience Category CLIA Kit Sensitivity 18.75 pg/mL Range Average Recovery (%)

E2F Transcription Factor 1, ELISA Kit - MBS048387 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E2F transcription factor 1, ELISA Kit - MBS753168 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 pg/mL.

E2F transcription factor 1, ELISA Kit - MBS755223 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E2F Transcription Factor 1, ELISA Kit - MBS053581 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E2F transcription factor 1, ELISA Kit - MBS753487 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E2F Transcription Factor 1, ELISA Kit - MBS090960 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E2F transcription factor 1, ELISA Kit - MBS754260 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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