Gene Symbol | XDH |
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Entrez Gene | 7498 |
Alt Symbol | XO, XOR |
Species | Human |
Gene Type | protein-coding |
Description | xanthine dehydrogenase |
Other Description | xanthine dehydrogenase/oxidase|xanthine oxidoreductase |
Swissprots | Q4PJ16 Q16712 Q16681 P47989 |
Accessions | AAF15890 AAX76512 AAY68219 CAW36700 CAW39049 CAW41215 CAW47231 CAW63651 CAW71881 CAW80373 CAW82865 CAW86283 CAY77138 CBC02653 CBC04906 CBC06866 CBC13019 CBC45853 CBC62270 CBC79202 CBC84152 CBC89109 EAX00479 P47989 AK130114 BC166696 AAI66696 CV574002 D11456 BAA02013 U06117 AAA75287 U39487 AAB08399 XM_011533095 XP_011531397 XM_011533096 XP_011531398 NM_000379 NP_000370 |
Function | Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro). {ECO:0000269|PubMed:17301077}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Peroxisome {ECO:0000250}. Secreted. |
Tissue Specificity | Detected in milk (at protein level). {ECO:0000269|Ref.12}. |
Top Pathways | Peroxisome, Caffeine metabolism, Purine metabolism, Drug metabolism - other enzymes |
Xanthine Oxidase (A-3) - sc-398548 from Santa Cruz Biotechnology
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Xanthine Oxidase (T-17) - sc-22006 from Santa Cruz Biotechnology
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Xanthine Oxidase (H-110) - sc-20991 from Santa Cruz Biotechnology
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Xanthine Oxidase (N-15) - sc-22005 from Santa Cruz Biotechnology
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Anti-Xanthine Oxidase antibody [EPR4605] - ab109235 from Abcam
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Anti-Xanthine Oxidase antibody [EPR4606] - ab133268 from Abcam
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Anti-Xanthine Oxidase antibody - N-terminal - ab176165 from Abcam
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Anti-XDH / Xanthine Oxidase Antibody - LS-C26419 from LifeSpan Bioscience
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Anti-XDH / Xanthine Oxidase Antibody (HRP) - LS-C26423 from LifeSpan Bioscience
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Anti-XDH / Xanthine Oxidase Antibody - LS-C86349 from LifeSpan Bioscience
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Anti-XDH / Xanthine Oxidase Antibody (Biotin) - LS-C147679 from LifeSpan Bioscience
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Anti-XDH / Xanthine Oxidase Antibody - LS-C147678 from LifeSpan Bioscience
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Anti-XDH / Xanthine Oxidase Antibody - LS-C147680 from LifeSpan Bioscience
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Anti-XDH / Xanthine Oxidase Antibody - LS-C193725 from LifeSpan Bioscience
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Anti-XDH / Xanthine Oxidase Antibody - LS-C209646 from LifeSpan Bioscience
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Anti-XDH / Xanthine Oxidase Antibody (HRP) - LS-C209661 from LifeSpan Bioscience
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Anti-XDH / Xanthine Oxidase Antibody (aa206-234, AP) - LS-C273683 from LifeSpan Bioscience
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Anti-XDH / Xanthine Oxidase Antibody (Biotin) - LS-C209675 from LifeSpan Bioscience
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Anti-XDH / Xanthine Oxidase Antibody (aa206-234, APC) - LS-C273685 from LifeSpan Bioscience
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Anti-XDH / Xanthine Oxidase Antibody (aa206-234, FITC) - LS-C273686 from LifeSpan Bioscience
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Anti-XDH / Xanthine Oxidase Antibody (aa206-234, PE) - LS-C273687 from LifeSpan Bioscience
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Anti-XDH / Xanthine Oxidase Antibody (aa213-242) - LS-C326386 from LifeSpan Bioscience
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Anti-XDH / Xanthine Oxidase Antibody (aa415-464) - LS-C186728 from LifeSpan Bioscience
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Anti-XDH / Xanthine Oxidase Antibody IHC-plus⢠- LS-B2214 from LifeSpan Bioscience
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Anti-XDH / Xanthine Oxidase Antibody (Internal, clone EPR4606) IHC-plus™ - LS-B11588 from LifeSpan Bioscience
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