Gene Symbol | XDH |
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Entrez Gene | 7498 |
Alt Symbol | XO, XOR |
Species | Human |
Gene Type | protein-coding |
Description | xanthine dehydrogenase |
Other Description | xanthine dehydrogenase/oxidase|xanthine oxidoreductase |
Swissprots | Q4PJ16 Q16712 Q16681 P47989 |
Accessions | AAF15890 AAX76512 AAY68219 CAW36700 CAW39049 CAW41215 CAW47231 CAW63651 CAW71881 CAW80373 CAW82865 CAW86283 CAY77138 CBC02653 CBC04906 CBC06866 CBC13019 CBC45853 CBC62270 CBC79202 CBC84152 CBC89109 EAX00479 P47989 AK130114 BC166696 AAI66696 CV574002 D11456 BAA02013 U06117 AAA75287 U39487 AAB08399 XM_011533095 XP_011531397 XM_011533096 XP_011531398 NM_000379 NP_000370 |
Function | Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro). {ECO:0000269|PubMed:17301077}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Peroxisome {ECO:0000250}. Secreted. |
Tissue Specificity | Detected in milk (at protein level). {ECO:0000269|Ref.12}. |
Top Pathways | Peroxisome, Caffeine metabolism, Purine metabolism, Drug metabolism - other enzymes |
Human Xanthine Oxidase protein fragment - ab159820 from Abcam
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XDH / Xanthine Oxidase Antibody Blocking Peptide - LS-E23096 from LifeSpan Bioscience
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XDH / Xanthine Oxidase Antibody Blocking Peptide - LS-E10039 from LifeSpan Bioscience
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Recombinant Human Xanthine Oxidase Protein - H00007498-Q01 from Novus Biologicals
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XDH-Antibody-N-term-Blocking-Peptide - BP9277a from Abgent, a WuXi AppTec company
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XDH - H00007498-Q01-10 from Acris Antibodies
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XDH - H00007498-Q01-25 from Acris Antibodies
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Recombinant Human XDH - XDH-851H from Creative Biomart
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Recombinant Xanthine Dehydrogenase (XDH) - RPC608Hu01 from Uscn Life Science Inc.
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Recombinant Xanthine Dehydrogenase (XDH) - RPC608Mu01 from Uscn Life Science Inc.
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Recombinant Xanthine Dehydrogenase (XDH) - RPC608Mu02 from Uscn Life Science Inc.
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Recombinant Xanthine Dehydrogenase (XDH) - RPC608Ra01 from Uscn Life Science Inc.
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Recombinant Xanthine Dehydrogenase (XDH) - RPC608Bo01 from Uscn Life Science Inc.
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Recombinant Xanthine Dehydrogenase (XDH) - RPC608Hu01 from Cloud-clone
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Recombinant Human Xanthine dehydrogenase/oxidase(XDH) ,partial - CSB-YP026189HU CSB-EP026189HU CSB-BP026189HU CSB-MP026189HU from Cusabio
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XDH Peptide - abx165033 from Abbexa
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XDH - TP319402 from Acris Antibodies
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Xanthine dehydrogenase/oxidase(XDH) ,partial, Recombinant Protein - MBS958091 from MyBioSource
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Recombinant Human XDH protein, His/GST-tagged - XDH-17H from Creative Biomart
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Recombinant Human XDH protein, MYC/DDK-tagged - XDH-18H from Creative Biomart
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XDH Peptide, Human - M34GP17565H from Creative Peptides
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Recombinant Xanthine Dehydrogenase (XDH) - RPU52169 from Biomatik
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XDH Recombinant Protein (OPCD07979) - OPCD07979 from Aviva Systems Biology
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Xanthine Oxidase Recombinant Protein Antigen - NBP2-56403PEP from Novus Biologicals
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Xanthine Oxidase Recombinant Protein Antigen - NBP2-57577PEP from Novus Biologicals
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