Gene Symbol | GTF2IRD1 |
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Entrez Gene | 9569 |
Alt Symbol | BEN, CREAM1, GTF3, MUSTRD1, RBAP2, WBS, WBSCR11, WBSCR12, hMusTRD1alpha1 |
Species | Human |
Gene Type | protein-coding |
Description | GTF2I repeat domain containing 1 |
Other Description | USE B1-binding protein|Williams-Beuren syndrome chromosome region 11|binding factor for early enhancer|general transcription factor 3|general transcription factor II-I repeat domain-containing protein 1|general transcription factor III|muscle TFII-I repeat domain-containing protein 1 alpha 1|slow-muscle-fiber enhancer-binding protein|williams-Beuren syndrome chromosomal region 12 protein |
Swissprots | Q9UHK8 Q8WVC4 Q9UHL9 Q9UI91 Q86UM3 O95444 Q75MX7 Q6DSU6 |
Accessions | AAP21877 AAS00361 AAS00362 EAW69599 EAW69600 EAW69601 Q9UHL9 AB209389 BAD92626 AF089107 AAF21796 AF104923 AAD27668 AF118270 AAD14687 AF151354 AAF19786 AF156489 AAF17358 AK308242 AY648295 AAT68469 BC018136 AAH18136 DQ891171 ABM82097 DQ894354 ABM85280 XM_006716182 XP_006716245 XM_006716183 XP_006716246 XM_011516713 XP_011515015 NM_001199207 NP_001186136 NM_005685 NP_005676 NM_016328 NP_057412 |
Function | May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8 (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Highly expressed in adult skeletal muscle, heart, fibroblast, bone and fetal tissues. Expressed at lower levels in all other tissues tested. |
Top Pathways | Herpes simplex infection, cGMP-PKG signaling pathway, Basal transcription factors |
Human GTF2IRD1 full length protein - ab160551 from Abcam
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Human GTF2IRD1 full length protein - ab160552 from Abcam
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Human GTF2IRD1 protein fragment - ab160553 from Abcam
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GTF3 / GTF2IRD1 Antibody Blocking Peptide - LS-E5594 from LifeSpan Bioscience
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GTF3 / GTF2IRD1 Antibody Blocking Peptide - LS-E11928 from LifeSpan Bioscience
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GTF3 / GTF2IRD1 Antibody Blocking Peptide - LS-E14164 from LifeSpan Bioscience
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GTF3 / GTF2IRD1 Antibody Blocking Peptide - LS-E14163 from LifeSpan Bioscience
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GTF3 / GTF2IRD1 Antibody Blocking Peptide - LS-E26142 from LifeSpan Bioscience
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Recombinant Human GTF2IRD1 Protein - H00009569-Q01 from Novus Biologicals
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GTF2IRD1 Recombinant Protein - H00009569-P01 from Novus Biologicals
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Recombinant Human GTF2IRD1 Protein - H00009569-P02 from Novus Biologicals
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GTF2IRD1-Antibody-N-term-Blocking-Peptide - BP18120a from Abgent, a WuXi AppTec company
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GTF2IRD1 blocking peptide - GTX89270-PEP from GeneTex
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GTF2IRD1 Peptide - AC21-0972-P from Abcore
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GTF2IRD1 / CREAM1 - H00009569-P01-10 from Acris Antibodies
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GTF2IRD1 / CREAM1 - H00009569-P01-25 from Acris Antibodies
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GTF2IRD1 / CREAM1 - H00009569-P02 from Acris Antibodies
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GTF2IRD1 / CREAM1 - H00009569-Q01-10 from Acris Antibodies
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GTF2IRD1 / CREAM1 - H00009569-Q01-25 from Acris Antibodies
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GTF2IRD1 Peptide - 45-714P from ProSci
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GTF2IRD1 fusion protein - Ag10761 from Proteintech Group
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GTF2IRD1 fusion protein - Ag10718 from Proteintech Group
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GTF2IRD1 fusion protein - ag0482 from Proteintech Group
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Recombinant Human GTF2IRD1, His-tagged - GTF2IRD1-13602H from Creative Biomart
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WBSCR11 (K94) Peptide - BS2161P from Bioworld Technology
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