CEBPB

Gene Symbol CEBPB
Entrez Gene 1051
Alt Symbol C/EBP-beta, IL6DBP, NF-IL6, TCF5
Species Human
Gene Type protein-coding
Description CCAAT/enhancer binding protein (C/EBP), beta
Other Description CCAAT/enhancer-binding protein beta|interleukin 6-dependent DNA-binding protein|nuclear factor NF-IL6|nuclear factor of interleukin 6|transcription factor 5
Swissprots P17676 Q9H4Z5 A8K671 Q96IH2
Accessions AAN86350 CAA36794 EAW75629 P17676 AF289608 AAL55792 AK291536 BAF84225 AW025406 BC005132 AAH05132 BC007538 AAH07538 BC021931 AAH21931 BU753628 D63161 BAA09637 DB457615 EU832661 ACE87752 EU832739 ACE87071 KJ161450 AHM26727 KJ161451 AHM26728 KJ161452 AHM26729 KJ161453 AHM26730 KJ161454 AHM26731 KJ161455 AHM26732 KJ161456 AHM26733 KJ161457 AHM26734 KJ161458 AHM26735 KJ161459 AHM26736 KJ161460 AHM26737 KJ161461 AHM26738 KJ161462 AHM26739 KJ161463 AHM26740 KJ161464 AHM26741 KJ161465 AHM26742 KJ161466 AHM26743 KJ161467 AHM26744 KJ161468 AHM26745 KJ161469 AHM26746 KJ161470 AHM26747 KJ161471 AHM26748 KJ161472 AHM26749 KJ161473 AHM26750 KJ161474 AHM26751 KJ161475 AHM26752 KJ161476 AHM26753 KJ161477 AHM26754 KJ161478 AHM26755 KJ161479 AHM26756 KJ161480 AHM26757 KJ161481 AHM26758 M98056 NM_001285878 NP_001272807 NM_001285879 NP_001272808 NM_005194 NP_005185
Function Important transcription factor regulating the expression of genes involved in immune and inflammatory responses. Binds to regulatory regions of several acute-phase and cytokines genes and probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Plays an important role in adipose tissue differentiation. Regulates the transcriptional induction of peroxisome proliferator-activated receptor gamma (PPARG) as well as other adipogenesis key player genes. {ECO:0000269|PubMed:20829347}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00978, ECO:0000269|PubMed:20829347}.
Tissue Specificity Expressed at low levels in the lung, kidney and spleen.
Top Pathways Tuberculosis, TNF signaling pathway, Transcriptional misregulation in cancer

Phospho-C/EBPβ (Thr235) Antibody - 3084 from Cell Signaling Technology

Prices $109.00, $287.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from adipocytes (differentiated 3T3-L1) treated with insulin for the indicated times, using Phospho-C/EBPbeta (Thr235) Antibody.

C/EBPβ (LAP) Antibody - 3087 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from COS cells, untransfected or transfected with human or mouse C/EBPbeta (LAP), using C/EBPbeta (LAP) Antibody.

C/EBP β (Δ 198) - sc-746 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
C/EBP β (Δ 198): sc-746. Immunoperoxidase staining of formalin-fixed, paraffin-embedded mouse liver tissue showing nuclear staining of select cells.

C/EBP β (H-7) - sc-7962 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
C/EBP β (H-7): sc-7962. Immunoperoxidase staining of formalin fixed, paraffin-embedded human breast tissue showing nuclear staining of glandular cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

C/EBP β (C-19) - sc-150 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
C/EBP β (C-19): sc-150. Western blot analysis of C/EBP β expression in control (A) and phorbol-induced (B) Jurkat cell nuclear extracts. C/EBP β fusion protein is shown as positive control (C).

C/EBP β (47A1) - sc-56637 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
C/EBP β (47A1): sc-56637. Western blot analysis of C/EBP β expression in HeLa (A) and Hep G2 (B) nuclear extracts.

Anti-CEBP Beta (phospho T188 + T235) antibody - ab192178 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CEBP Beta (phospho T188 + T235) antibody (ab192178) at 1/500 dilutionLane 1 : HepG2 whole cell lysates with antigen-specific peptideLane 2 : HepG2 whole cell lysatesLysates/proteins at 12.5 µg per lane.

Anti-CEBP Beta (phospho T235 + T188) antibody - ab52194 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab52194 staining CEBP Beta (phospho T335 + T188) in Human MDA-MB-468 breast cancer cells by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with 4% paraformaldehyde + 2% sucrose and permeabilized with 0.5% Triton X-100 in PBS. Samples were incubated with primary antibody (in PBS + 1% BSA) for 30 minutes at 37°C.From left - DAPI (blue), MUC1-C (green), CERP Beta phospho T335 + T188 (red), Merge, Zoom.Top - CshRNA, Bottom - MUC1shRNA.Magnification - x63, Zoom (from pink boxes) - x252.

Anti-CEBP Beta antibody - ab53138 from Abcam

Prices $379.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CEBP Beta antibody (ab53138) at 1/300 dilutionLane 1 : NIH/3T3 cell extractLane 2 : NIH/3T3 cell extract with immunizing peptide

Anti-CEBP Beta antibody - ab137510 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CEBP Beta antibody (ab137510) at 1/1000 dilution + A431 whole cell lysate at 30 µg

Anti-CEBP Beta antibody - ab131542 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CEBP Beta antibody (ab131542) at 1/500 dilutionLane 1 : Rat brain tissue lysateLane 2 : Mouse brain tissue lysateLane 3 : 293 cell lysate

Anti-CEBP Beta antibody - ab65065 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CEBP Beta antibody (ab65065) at 1/500 dilutionLane 1 : extracts from Jurkat cellsLane 2 : extracts from Jurkat cells with immunizing peptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-CEBP Beta antibody [18F8] - ChIP Grade - ab15049 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 18F8

Anti-CEBP Beta antibody [47A1] - ab33481 from Abcam

Prices $378.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 47A1
Anti-CEBP Beta antibody [47A1] (ab33481) at 1/1000 dilution + NIH 3T3 cell lysate at 30 µgSecondaryGoat anti-mouse secondary antibody conjugated to HRPdeveloped using the ECL technique

Anti-CEBP Beta antibody [A16] - ab18336 from Abcam

Host Mouse
Clonality Monoclonal
Clone A16
ab18336 staining mouse microglia cells by ICC/IF.  Cells were PFA fixed and permeabilized in 0.5% Triton prior to blocking in 5% serum for 30 minutes at 37°C.  The primary antibody was diluted 1/100 and incubated with the sample for 1 hour at 37°C.  An Alexa Fluor® 488 goat anti-mouse antibody (ab150113) diluted 1/500 was used as the secondary.  The images show clear nuclear CEBP beta staining in microglial cells treated with LPS.See Abreview

Anti-CEBP Beta antibody [E298] - ab32098 from Abcam

Host Rabbit
Clonality Monoclonal
Clone E298
Anti-CEBP Beta antibody [E298] (ab32098) at 1/2000 dilution + PC-12 cell lysate.

Anti-CEBP Beta antibody [E298] (HRP) - ab194710 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone E298
Anti-CEBP Beta antibody [E298] (HRP) (ab194710) at 1/1000 dilution + PC12 (Rat adrenal pheochromocytoma cell line) Whole Cell Lysate at 10 µgdeveloped using the ECL techniquePerformed under reducing conditions.

Anti-CEBP Beta antibody [E299] - ab32358 from Abcam

Prices $401.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone E299
Overlay histogram showing HeLa cells stained with ab32358 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab32358, 1/1000 dilution) for 30 min at 22°C. The secondary antibody used was DyLight® 488 goat anti-rabbit IgG (H+L) (ab96899) at 1/500 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) (1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-C/EBP Beta / CEBPB Antibody (aa39-78, clone 21A1) IHC-plus™ - LS-B1688 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 21A1
Anti-CEBPB / CEBP Beta antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1688 concentration 10 ug/ml.

Anti-C/EBP Beta / CEBPB Antibody (aa271-298) - LS-C168649 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human lung carcinoma reacted with CEBPB Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-C/EBP Beta / CEBPB Antibody (aa99-131) - LS-C344321 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysate from R. liver cell line with rat-Cebpb-S105. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35 ug.

Anti-C/EBP Beta / CEBPB Antibody (phospho-Thr235/Thr188) - LS-C198706 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human breast carcinoma, using C/EBP-beta (Phospho-Thr235/188) Antibody. The sample on the right was incubated with synthetic peptide.

Anti-C/EBP Beta / CEBPB Antibody (aa1-200) - LS-C344026 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
CEBP Beta antibody IHC-paraffin: Human Placenta Tissue.

Anti-C/EBP Beta / CEBPB Antibody (clone 47A1) IHC-plus™ - LS-B2926 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 47A1
Anti-CEBPB / CEBP Beta antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2926 concentration 10 ug/ml.

Anti-C/EBP Beta / CEBPB Antibody (phospho-Ser105) - LS-C14431 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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