KCNA4

Gene Symbol KCNA4
Entrez Gene 3739
Alt Symbol HBK4, HK1, HPCN2, HUKII, KCNA4L, KCNA8, KV1.4, PCN2
Species Human
Gene Type protein-coding
Description potassium channel, voltage gated shaker related subfamily A, member 4
Other Description cardiac potassium channel|fetal skeletal muscle potassium channel|potassium channel 2|potassium voltage-gated channel subfamily A member 4|potassium voltage-gated channel, shaker-related subfamily, member 4|rapidly inactivating potassium channel|shaker-related potassium channel Kv1.4|type A potassium channel|voltage-gated K(+) channel HuKII|voltage-gated potassium channel HBK4|voltage-gated potassium channel HK1|voltage-gated potassium channel subunit Kv1.4
Swissprots P22459
Accessions P22459 AK311228 AK313662 BC166685 AAI66685 BE467209 DA328650 L02751 AAA36140 M55514 AAA60034 M60450 AAA61275 NM_002233 NP_002224
Function Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane (PubMed:19912772, PubMed:8495559). Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel (PubMed:8495559). Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation. In vivo, membranes probably contain a mixture of heteromeric potassium channel complexes, making it difficult to assign currents observed in intact tissues to any partic
Subcellular Location Cell membrane {ECO:0000269|PubMed:17156368, ECO:0000269|PubMed:19912772, ECO:0000269|PubMed:19968958, ECO:0000269|PubMed:8495559}; Multi-pass membrane protein {ECO:0000305}. Cell projection, axon {ECO:0000250|UniProtKB:P15385}.
Tissue Specificity Detected in heart ventricle. {ECO:0000269|PubMed:2001794}.

KV1.4 (C-20) - sc-16180 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

KV1.4 (F-20) - sc-16179 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
KV1.4 (F-20): sc-16179. Western blot analysis of KV1.4 expression in SK-N-SH (A) and U-87 MG (B) whole cell lysates.

Anti-Kv1.4 antibody - ab65788 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-Kv1.4 antibody [S13-31] - ab99332 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S13-31
Immunohistochemical detection of Kv1.4 using ab99332 in Mouse brain. Weak positivity of some neurons with a bit of non-specImmunofluorescentic background.

Anti-Kv1.4 antibody - C-terminal - ab156162 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Kv1.4 antibody - C-terminal (ab156162) at 1/100 dilution + 293 cell lysate at 35 µg

Anti-KCNA4 / Kv1.4 Antibody - LS-C26581 from LifeSpan Bioscience

Prices $330.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KCNA4 / Kv1.4 Antibody - LS-C26739 from LifeSpan Bioscience

Prices $330.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KCNA4 / Kv1.4 Antibody (N-Terminus) - LS-C8391 from LifeSpan Bioscience

Prices $515.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KCNA4 / Kv1.4 Antibody (N-Terminus) - LS-C144746 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNA4 / Kv1.4 Antibody (aa14-37, clone S13-31, Atto 488) - LS-C227926 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S13-31

Anti-KCNA4 / Kv1.4 Antibody (aa14-37, clone S13-31, Atto 390) - LS-C227925 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S13-31

Anti-KCNA4 / Kv1.4 Antibody (aa14-37, clone S13-31, Atto 565) - LS-C227927 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S13-31

Anti-KCNA4 / Kv1.4 Antibody (aa14-37, clone S13-31, Atto 633) - LS-C227929 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S13-31

Anti-KCNA4 / Kv1.4 Antibody (aa14-37, clone S13-31, Atto 680) - LS-C227931 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S13-31

Anti-KCNA4 / Kv1.4 Antibody (aa14-37, clone S13-31, Atto 594) - LS-C227928 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S13-31

Anti-KCNA4 / Kv1.4 Antibody (aa14-37, clone S13-31, Atto 655) - LS-C227930 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S13-31

Anti-KCNA4 / Kv1.4 Antibody (aa14-37, clone S13-31, AP) - LS-C227933 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S13-31

Anti-KCNA4 / Kv1.4 Antibody (N-Terminus) - LS-C152845 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
WB: Rabbit anti-Kv1.4 (LS-C152845) Western blotting of rat membrane proteins. V = ventricle and B = brain.

Anti-KCNA4 / Kv1.4 Antibody (aa14-37, clone S13-31, Atto 700) - LS-C227932 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S13-31

Anti-KCNA4 / Kv1.4 Antibody (aa14-37, clone S13-31, APC) - LS-C227934 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S13-31

Anti-KCNA4 / Kv1.4 Antibody (aa14-37, clone S13-31, FITC) - LS-C227936 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S13-31

Anti-KCNA4 / Kv1.4 Antibody (aa14-37, clone S13-31, Biotin) - LS-C227935 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S13-31

Anti-KCNA4 / Kv1.4 Antibody (aa14-37, clone S13-31, PE-Atto 594) - LS-C227938 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S13-31

Anti-KCNA4 / Kv1.4 Antibody (aa14-37, clone S13-31, RPE) - LS-C227940 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S13-31

Anti-KCNA4 / Kv1.4 Antibody (aa14-37, clone S13-31, SA) - LS-C227941 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S13-31
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