Ace

Gene Symbol Ace
Entrez Gene 11421
Alt Symbol AW208573, CD143
Species Mouse
Gene Type protein-coding
Description angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Other Description angiotensin-converting enzyme|dipeptidyl carboxypeptidase I|dipeptidyl peptidase|kininase II
Swissprots P09470 Q6GTS2 P22967
Accessions AAA37151 AAP03650 EDL34253 EDL34254 EDL34255 P09470 AK087056 BAC39791 AK154632 BAE32728 AK161020 BAE36151 AK164780 BC034367 AAH34367 BC040404 AAH40404 BC052531 AAH52531 BC083109 AAH83109 BC110362 AAI10363 BY197083 BY210311 J03940 AAA37146 J04946 AAA37147 J04947 AAA37148 M55333 AAA37149 NM_001281819 NP_001268748 NM_009598 NP_033728 NM_207624 NP_997507
Function Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. This GPIase activity seems to be crucial for the egg-binding ability of the sperm. {ECO:0000269|PubMed:15665832, ECO:0000269|PubMed:7753170, ECO:0000269|PubMed:8642790}.
Subcellular Location Angiotensin-converting enzyme, soluble form: Secreted {ECO:0000250}.
Tissue Specificity Testis-specific isoform is expressed in spermatocytes, adult testis.
Top Pathways Hypertrophic cardiomyopathy (HCM), Chagas disease (American trypanosomiasis), Renin-angiotensin system

ACE CRISPR/Cas9 KO Plasmid (m) - sc-418942 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACE HDR Plasmid (m) - sc-418942-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACE Double Nickase Plasmid (m) - sc-418942-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACE Double Nickase Plasmid (m2) - sc-418942-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACE CRISPR Activation Plasmid (m) - sc-418942-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACE CRISPR Activation Plasmid (m2) - sc-418942-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACE Lentiviral Activation Particles (m) - sc-418942-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACE Lentiviral Activation Particles (m2) - sc-418942-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACE siRNA (m) - sc-29627 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

ACE shRNA Plasmid (m) - sc-29627-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

ACE shRNA (m) Lentiviral Particles - sc-29627-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

CompoZr® Knockout ZFN Kit - CKOZFN26143 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND26143 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ACE siRNA (Mouse) - CRM0017 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

ACE - MBS8210081 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse ACE (NM_009598.2) - SHH230210 from Creative biogene

Category siRNA
Species Reactivities Mouse

ACE shRNA Plasmid (Mouse) - CHM0017 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse
Search more