Gene Symbol | CBX6 |
---|---|
Entrez Gene | 23466 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | chromobox homolog 6 |
Other Description | chromobox protein homolog 6 |
Swissprots | Q96EM5 O95503 A8KAH0 |
Accessions | CBX47622 EAW60276 O95503 AK094829 BAG52939 AK293035 BAF85724 BC012111 AAH12111 BC064900 AAH64900 CD625491 DQ893667 ABM84593 DQ895787 ABM86713 HY128779 HY151719 XM_011530024 XP_011528326 NM_001303494 NP_001290423 NM_014292 NP_055107 |
Function | Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. {ECO:0000269|PubMed:21282530}. |
Subcellular Location | Nucleus {ECO:0000250}. |