CBX6

Gene Symbol	CBX6
Entrez Gene	23466
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	chromobox homolog 6
Other Description	chromobox protein homolog 6
Swissprots	Q96EM5 O95503 A8KAH0
Accessions	CBX47622 EAW60276 O95503 AK094829 BAG52939 AK293035 BAF85724 BC012111 AAH12111 BC064900 AAH64900 CD625491 DQ893667 ABM84593 DQ895787 ABM86713 HY128779 HY151719 XM_011530024 XP_011528326 NM_001303494 NP_001290423 NM_014292 NP_055107
Function	Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. {ECO:0000269\|PubMed:21282530}.
Subcellular Location	Nucleus {ECO:0000250}.

CBX6 (H-1) - sc-393040 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

CBX6 (H-1): sc-393040. Western blot analysis of CBX6 expression in non-transfected: sc-117752 (A) and mouse CBX6 transfected: sc-119053 (B) 293T whole cell lysates and NIH/3T3 (C) and 3611-RF (D) nuclear extracts.

CBX6 (P-13) - sc-86355 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	100 µg/ml
Host	Rabbit
Clonality	Polyclonal

CBX6 (P-13): sc-86355. Western blot analysis of CBX6 expression in HeLa whole cell lysate.

CBX6 (E-16) - sc-86354 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	100 µg/ml
Host	Rabbit
Clonality	Polyclonal

CBX6 (E-16): sc-86354. Western blot analysis of CBX6 expression in non-transfected: sc-117752 (A) and mouse CBX6 transfected: sc-119053 (B) 293T whole cell lysates.

CBX6 (S-12) - sc-86356 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	100 µg/ml
Host	Rabbit
Clonality	Polyclonal

CBX6 (S-12): sc-86356. Western blot analysis of CBX6 expression in HeLa nuclear extract.

CBX6 (W-22) - sc-133442 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	100 µg/ml
Host	Rabbit
Clonality	Polyclonal

CBX6 (W-22): sc-133442. Western blot analysis of CBX6 expression in Jurkat whole cell lysate.

Anti-CBX6 + CBX8 antibody - ab24332 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

All lanes : Anti-CBX6 + CBX8 antibody (ab24332)Lane 1 : 293Lane 2 : 293 stably expressing cbx6Lane 3 : 293 stably expressing cbx7Lane 4 : 293 stably expressing cbx8Lane 5 : 293Lane 6 : 293 stably expressing cbx6Lane 7 : 293 stably expressing cbx7Lane 8 : 293 stably expressing cbx8SecondaryNon Abcam, antigoat.

Anti-Cbx6 antibody - ab65148 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-Cbx6 antibody (ab65148) at 1/500 dilutionLane 1 : 293 cell extractLane 2 : HepG2 cell extractLane 3 : HepG2 cell extract with immunising peptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-Cbx6 antibody - ab113211 from Abcam

Prices	$428.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

ab113211 at 1/250 dilution staining Cbx6 in Human prostate carcinoma by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining

Anti-Cbx6 antibody - ab114124 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Detection of Cbx6 by Western Blot of Immunprecipitate. An antibody to Cbx6 at 1µg/ml staining Cbx6 in HeLa whole cell lysate immunoprecipitated using ab114124 at 10µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Detection: Chemiluminescence with exposure time of 30 seconds.

Anti-Cbx6 antibody [EPR16463] - C-terminal - ab195235 from Abcam

Prices	$357.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR16463

All lanes : Anti-Cbx6 antibody [EPR16463] - C-terminal (ab195235) at 1/1000 dilutionLane 1 : Mouse brain lysateLane 2 : Mouse kidney lysateLane 3 : Mouse spleen lysateLane 4 : Rat brain lysateLane 5 : Rat kidney lysateLane 6 : Rat spleen lysateLane 7 : C6 cell lysateLane 8 : RAW 264.7 cell lysateLane 9 : PC12 cell lysateLane 10 : NIH 3T3 cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Anti-Cbx6 antibody - C-terminal - ab135117 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-Cbx6 antibody - C-terminal (ab135117) at 1/1000 dilution + HepG2 total cell extract

Anti-CBX6 Antibody - LS-C125267 from LifeSpan Bioscience

Prices	$465.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CBX6 Antibody (Lys18) - LS-C191929 from LifeSpan Bioscience

Prices	$345.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CBX6 Antibody (aa362-412) - LS-C289036 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CBX6 Antibody (aa10-59) - LS-C118737 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of extracts from 293/HepG2 cells, using CBX6 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-CBX6 Antibody (aa250-300) - LS-C286857 from LifeSpan Bioscience

Prices	$415.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Detection of Human CBX6 by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-CBX6 used at a dilution of 1:250.

Anti-CBX6 Antibody (N-Terminus) - LS-C30986 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

CBX6 antibody LS-C30986 was used in IHC to stain formalin-fixed, paraffin-embedded human muscle.

Anti-CBX6 Antibody (aa250-300) - LS-C289034 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CBX6 Antibody - LS-C334116 from LifeSpan Bioscience

Prices	$305.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Western blot analysis of extracts of HepG2 cell line, using CBX6 antibody.

Anti-CBX6 Antibody (aa321-370) - LS-C30988 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CBX6/CBX8 Antibody (N-Terminus) - LS-C54620 from LifeSpan Bioscience

Prices	$335.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

CBX6 Antibody - NBP1-28731 from Novus Biologicals

Prices	$359.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: CBX6 Antibody [NBP1-28731] - Samples: Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 ug) and mouse NIH3T3 (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-CBX6 antibody NBP1-28731 used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 10 ug/mg lysate. CBX6 was also immunoprecipitated by rabbit anti-CBX6 antibody NBP1-28686, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B).

CBX6 Antibody - H00023466-B01 from Novus Biologicals

Host	Mouse
Clonality	Polyclonal

Western Blot: CBX6 Antibody [H00023466-B01] - analysis of CBX6 expression in transfected 293T cell line by CBX6 MaxPab polyclonal antibody (B01). Lane 1: CBX6 transfected lysate (43.90 KDa). Lane 2: Non-transfected lysate.

CBX6 Antibody - NBP1-28686 from Novus Biologicals

Prices	$359.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunoprecipitation: CBX6 Antibody [NBP1-28686] - Detection of Human CBX6 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-CBX6 antibody NBP1-28686 used for IP at 10 mcg/mg lysate. CBX6 was also immunoprecipitated by rabbit anti-CBX6 antibody A302-283A, which recognizes an upstream epitope. For blotting immunoprecipitated CBX6, A302-283A was used at 1 mcg/ml, and the ReliaBLOT (Copyright) Reagents and Procedures were incorporated. Detection: Chemiluminescence with an exposure time of 30 seconds.

CBX6 Antibody - NBP1-71964 from Novus Biologicals

Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry: CBX6 Antibody [NBP1-71964]-FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-CBX6 used at a dilution of 1:250.

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