Gene Symbol | CBX6 |
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Entrez Gene | 23466 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | chromobox homolog 6 |
Other Description | chromobox protein homolog 6 |
Swissprots | Q96EM5 O95503 A8KAH0 |
Accessions | CBX47622 EAW60276 O95503 AK094829 BAG52939 AK293035 BAF85724 BC012111 AAH12111 BC064900 AAH64900 CD625491 DQ893667 ABM84593 DQ895787 ABM86713 HY128779 HY151719 XM_011530024 XP_011528326 NM_001303494 NP_001290423 NM_014292 NP_055107 |
Function | Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. {ECO:0000269|PubMed:21282530}. |
Subcellular Location | Nucleus {ECO:0000250}. |
CBX6 CRISPR/Cas9 KO Plasmid (h) - sc-405594 from Santa Cruz Biotechnology
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CBX6 HDR Plasmid (h) - sc-405594-HDR from Santa Cruz Biotechnology
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CBX6 Double Nickase Plasmid (h) - sc-405594-NIC from Santa Cruz Biotechnology
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CBX6 Double Nickase Plasmid (h2) - sc-405594-NIC-2 from Santa Cruz Biotechnology
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CBX6 CRISPR Activation Plasmid (h) - sc-405594-ACT from Santa Cruz Biotechnology
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CBX6 CRISPR Activation Plasmid (h2) - sc-405594-ACT-2 from Santa Cruz Biotechnology
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CBX6 Lentiviral Activation Particles (h) - sc-405594-LAC from Santa Cruz Biotechnology
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CBX6 Lentiviral Activation Particles (h2) - sc-405594-LAC-2 from Santa Cruz Biotechnology
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CBX6 siRNA (h) - sc-72815 from Santa Cruz Biotechnology
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CBX6 shRNA Plasmid (h) - sc-72815-SH from Santa Cruz Biotechnology
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CBX6 shRNA (h) Lentiviral Particles - sc-72815-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU047411 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5430 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5430 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10847 from Sigma-Aldrich
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CBX6 siRNA (Human) - CRH8287 from Cohesion Biosciences
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CBX6 - MBS8216881 from MyBioSource
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shRNA set against Human CBX6 (NM_014292.3) - SHH255545 from Creative biogene
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shRNA set against Human CBX6(NM_014292.3) - SHG145549 from Creative biogene
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CBX6 shRNA Plasmid (Human) - CHH8287 from Cohesion Biosciences
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CBX6 miRNA 3'UTR clone - MiUTR1H-01711 from Creative biogene
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