Gene Symbol | Ska3 |
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Entrez Gene | 219114 |
Alt Symbol | F630043A04Rik |
Species | Mouse |
Gene Type | protein-coding |
Description | spindle and kinetochore associated complex subunit 3 |
Other Description | spindle and kinetochore-associated protein 3 |
Swissprots | Q149T5 Q8C263 Q149T6 |
Accessions | EDL36162 EDL36163 Q8C263 AK089223 BAC40798 AK138255 AK158142 AK166171 AK199129 AK213217 AK217625 BC117500 AAI17501 BC117501 AAI17502 XM_006518859 XP_006518922 XR_383169 NM_198605 NP_941007 |
Function | Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the microtubule-stimulated oligomerization (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000250}. Note=Localizes to the outer kinetochore and spindle microtubules during mitosis in a NDC80 complex-dependent manner. {ECO:0000250}. |
Recombinant Mouse Spindle and kinetochore-associated protein 3(Ska3) - CSB-YP806483MO CSB-EP806483MO CSB-BP806483MO CSB-MP806483MO from Cusabio
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Recombinant Mouse SKA3 Protein - SKA3-15169M from Creative Biomart
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Spindle and kinetochore-associated protein 3 (Ska3), Recombinant Protein - MBS1334666 from MyBioSource
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