Prkcg

Gene Symbol	Prkcg
Entrez Gene	24681
Alt Symbol	PKC, PKCI, Prkc, Prkcc, RATPKCI
Species	Rat
Gene Type	protein-coding
Description	protein kinase C, gamma
Other Description	PKC-gamma|protein kinase C gamma type|protein kinase C type I (gamma type)
Swissprots	P63319 Q5FWS3
Accessions	AAA41873 EDL84948 P63319 BC089226 AAH89226 M13707 AAA41874 X07287 CAA30267 XM_006228014 XP_006228076 NM_012628 NP_036760
Function	Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays diverse roles in neuronal cells and eye tissues, such as regulation of the neuronal receptors GRIA4/GLUR4 and GRIN1/NMDAR1, modulation of receptors and neuronal functions related to sensitivity to opiates, pain and alcohol, mediation of synaptic function and cell survival after ischemia, and inhibition of gap junction activity after oxidative stress. Binds and phosphorylates GRIA4/GLUR4 glutamate receptor and regulates its function by increasing plasma membrane-associated GRIA4 expression. In primary cerebellar neurons treated with the agonist 3,5-dihyidroxyphenylglycine, functions downstream of the metabotropic glutamate receptor GRM5/MGLUR5 and phosphorylates GRIN1/NMDAR1 receptor which plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. May be involved in the regulation of hippocampal long-term potentiation (LTP), but ma
Subcellular Location	Cytoplasm {ECO:0000250|UniProtKB:P63318}. Cytoplasm, perinuclear region. Cell membrane {ECO:0000269|PubMed:12471040, ECO:0000269|PubMed:14688616}; Peripheral membrane protein. Cell junction, synapse, synaptosome {ECO:0000269|PubMed:14688616}. Cell projection, dendrite {ECO:0000269|PubMed:10336135}. Note=Translocates to synaptic membranes on stimulation. {ECO:0000269|PubMed:14688616}.
Top Pathways	Inflammatory mediator regulation of TRP channels, Oxytocin signaling pathway, Thyroid hormone synthesis, Retrograde endocannabinoid signaling, MicroRNAs in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Protein kinase C gamma type, Prkcg, Rat, ELISA Kit - E8823r from ARP American Research Products Category ELISA Kit Prices $660.00 Sizes 96 t

Rat PKC ELISA Kit - RP0675 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

proteinkinaseC (PKC), ELISA Kit - MBS265505 from MyBioSource Category ELISA Kit Prices $290.00, $450.00, $1,755.00, $3,150.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.06 ng/ml. Range 20 ng/ml-0.312 ng/ml

proteinkinaseC (PKC), ELISA Kit - MBS2602028 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

proteinkinaseC (PKC), ELISA Kit - MBS269389 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

proteinkinaseC (PKC), ELISA Kit - MBS269666 from MyBioSource Category ELISA Kit Prices $275.00, $420.00, $1,615.00, $2,880.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.06 ng/ml. Range 20 ng/ml-0.312 ng/ml

proteinkinaseC (PKC), ELISA Kit - MBS264812 from MyBioSource Category ELISA Kit Prices $290.00, $450.00, $1,755.00, $3,150.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.06 ng/ml. Range 20 ng/ml-0.312 ng/ml

proteinkinaseC (PKC), ELISA Kit - MBS264081 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

proteinkinaseC (PKC), ELISA Kit - MBS263591 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

proteinkinaseC (PKC) - MBS264692 from MyBioSource Category ELISA Kit Prices $315.00, $490.00 Sizes 48 strip wells, 96 strip wells

Rat PKC(Protein Kinase C) ELISA Kit - E-EL-R0815 from Elabscience Category ELISA Kit Sensitivity 9.38 pg/mL Range 15.63—1000 pg/mL

Rat PKC(Protein Kinase C)CLIA Kit - E-CL-R0573 from Elabscience Category CLIA Kit Sensitivity 4.69 pg/mL Range Average Recovery (%)

Rat protein kinase C ELISA - E02P0668 from BlueGene Biotech Category ELISA Kit Sensitivity 0.1 ng/mL

Rat PKC(Protein Kinase C) ELISA Kit - E-EL-R0815 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 9.38 pg/mL Range 15.63~1000 pg/mL

Rat PKC / Protein Kinase C ELISA Kit (Sandwich ELISA) - LS-F23227 from LifeSpan Bioscience Category ELISA Kit Prices $590.00 Sizes 1 plate Sensitivity 9.375 pg/ml Range 0.313-20 ng/ml

PKC (Protein Kinase C), CLIA Kit - MBS2532177 from MyBioSource Category CLIA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 4.688pg/mL Range 7.813-500pg/mL

Rat PKC / Protein Kinase C ELISA Kit (Competitive EIA) - LS-F28061 from LifeSpan Bioscience Category ELISA Kit Prices $870.00 Sizes 1 plate Sensitivity 0.1 ng/ml Range 0.313-20 ng/ml

PKC - EKR2538 from Nordic BioSite Sensitivity 9.375pg/ml Range 15.625--1000pg/ml

Rat Prkcg ELISA Kit - E087866 from Biobool Category ELISA Kit

PRKCG ELISA Kit (Rat) (OKEH05969) - OKEH05969 from Aviva Systems Biology Category ELISA Kit Prices $470.00 Sizes 96 wells Sensitivity 0.078 ng/mL Range 0.156-10 ng/mL

Rat PKC ELISA Kit - ERP0675 from ABclonal Category ELISA Kit Prices $495.00 Sizes 96 t

kinase C gamma type, ELISA Kit - MBS2881768 from MyBioSource Category ELISA Kit Prices $430.00, $570.00, $2,515.00, $4,520.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rat PKC (Protein Kinase C) ELISA Kit - EKE62256 from Biomatik Category ELISA Kit Prices $609.00 Sizes 96 tests Sensitivity 9.38 pg/mL Range 15.63-1000 pg/mL

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