Prkcg

Gene Symbol Prkcg
Entrez Gene 24681
Alt Symbol PKC, PKCI, Prkc, Prkcc, RATPKCI
Species Rat
Gene Type protein-coding
Description protein kinase C, gamma
Other Description PKC-gamma|protein kinase C gamma type|protein kinase C type I (gamma type)
Swissprots P63319 Q5FWS3
Accessions AAA41873 EDL84948 P63319 BC089226 AAH89226 M13707 AAA41874 X07287 CAA30267 XM_006228014 XP_006228076 NM_012628 NP_036760
Function Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays diverse roles in neuronal cells and eye tissues, such as regulation of the neuronal receptors GRIA4/GLUR4 and GRIN1/NMDAR1, modulation of receptors and neuronal functions related to sensitivity to opiates, pain and alcohol, mediation of synaptic function and cell survival after ischemia, and inhibition of gap junction activity after oxidative stress. Binds and phosphorylates GRIA4/GLUR4 glutamate receptor and regulates its function by increasing plasma membrane-associated GRIA4 expression. In primary cerebellar neurons treated with the agonist 3,5-dihyidroxyphenylglycine, functions downstream of the metabotropic glutamate receptor GRM5/MGLUR5 and phosphorylates GRIN1/NMDAR1 receptor which plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. May be involved in the regulation of hippocampal long-term potentiation (LTP), but ma
Subcellular Location Cytoplasm {ECO:0000250|UniProtKB:P63318}. Cytoplasm, perinuclear region. Cell membrane {ECO:0000269|PubMed:12471040, ECO:0000269|PubMed:14688616}; Peripheral membrane protein. Cell junction, synapse, synaptosome {ECO:0000269|PubMed:14688616}. Cell projection, dendrite {ECO:0000269|PubMed:10336135}. Note=Translocates to synaptic membranes on stimulation. {ECO:0000269|PubMed:14688616}.
Top Pathways Inflammatory mediator regulation of TRP channels, Oxytocin signaling pathway, Thyroid hormone synthesis, Retrograde endocannabinoid signaling, MicroRNAs in cancer

PRKCG antibody - PAB13638 from Acris Antibodies

Prices $420.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Purified anti-PKCα Phospho (Thr638) Antibody - 649101 from Biolegend

Prices $150.00, $295.00
Sizes 25 µl (5 Western blots), 100 µl (20 Western blots)
Host Rabbit
Clone Poly6491
Jurkat total cell lysates were resloved by electrophoresis, transferred to nitrocellulose and probed either with anti-phosphor-PKA (T638) antibody solely (Lane 1), anti-phosphor-PKA (T638) antibody plus phosphor-peptide (Lane 2), or with the anti-phosphor-PKA (T638) antibody plus non-phosphor-peptide (Lane 3). Proteins were visualized using an HRP donkey anti-rabbit secondary antibody and a chemiluminescence detection system.

Anti-Protein Kinase C Gamma (PKCg) - 20-2669 from ARP American Research Products

Prices $319.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

PKC, Monoclonal Antibody - MBS440096 from MyBioSource

Prices $340.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

PRKCG, Polyclonal Antibody - MBS624568 from MyBioSource

Prices $550.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Rabbit polyclonal antibody to Protein kinase C gamma (665-685): Affinity purified - R-1142-100 from Biosensis

Prices $297.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Monoclonal Antibody to Protein Kinase C Gamma (PKCg) - MAA419Ra21 from Cloud-clone

Host Mouse
Clonality Monoclonal

Polyclonal Antibody to Protein Kinase C Gamma (PKCg) - PAA419Ra01 from Cloud-clone

Host Rabbit
Clonality Polyclonal

Biotin-Linked Antibody to Protein Kinase C Gamma (PKCg) - PAA419Ra71 from Cloud-clone

Host Rabbit
Clonality Polyclonal

FITC-Linked Antibody to Protein Kinase C Gamma (PKCg) - PAA419Ra81 from Cloud-clone

Host Rabbit
Clonality Polyclonal

PRKCG antibody - TA328093 from Acris Antibodies

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Clone Poly6491
Jurkat total cell lysates were resloved by electrophoresis, transferred to nitrocellulose and probed either with anti-phosphor-PKA (T638) antibody solely (Lane 1), anti-phosphor-PKA (T638) antibody plus phosphor-peptide (Lane 2), or with the anti-phosphor-PKA (T638) antibody plus non-phosphor-peptide (Lane 3). Proteins were visualized using an HRP donkey anti-rabbit secondary antibody and a chemiluminescence detection system.

PRKCG antibody - TA352393 from Acris Antibodies

Prices $280.00
Sizes 25 µl
Host Rabbit
Clonality Monoclonal
Clone Poly6491
Jurkat total cell lysates were resloved by electrophoresis, transferred to nitrocellulose and probed either with anti-phosphor-PKA (T638) antibody solely (Lane 1), anti-phosphor-PKA (T638) antibody plus phosphor-peptide (Lane 2), or with the anti-phosphor-PKA (T638) antibody plus non-phosphor-peptide (Lane 3). Proteins were visualized using an HRP donkey anti-rabbit secondary antibody and a chemiluminescence detection system.

PKC gamma, Polyclonal Antibody - MBS7602718 from MyBioSource

Prices $265.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

PKC gamma, Polyclonal Antibody - MBS2539159 from MyBioSource

Prices $110.00, $150.00, $225.00, $360.00
Sizes 20 µl, 60 µl, 120 µl, 200 µl
Host Rabbit
Clonality Polyclonal

PKC gamma, Polyclonal Antibody - MBS2536167 from MyBioSource

Prices $110.00, $150.00, $225.00, $360.00
Sizes 20 µl, 60 µl, 120 µl, 200 µl
Host Rabbit
Clonality Polyclonal
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