Prkcg

Gene Symbol Prkcg
Entrez Gene 24681
Alt Symbol PKC, PKCI, Prkc, Prkcc, RATPKCI
Species Rat
Gene Type protein-coding
Description protein kinase C, gamma
Other Description PKC-gamma|protein kinase C gamma type|protein kinase C type I (gamma type)
Swissprots P63319 Q5FWS3
Accessions AAA41873 EDL84948 P63319 BC089226 AAH89226 M13707 AAA41874 X07287 CAA30267 XM_006228014 XP_006228076 NM_012628 NP_036760
Function Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays diverse roles in neuronal cells and eye tissues, such as regulation of the neuronal receptors GRIA4/GLUR4 and GRIN1/NMDAR1, modulation of receptors and neuronal functions related to sensitivity to opiates, pain and alcohol, mediation of synaptic function and cell survival after ischemia, and inhibition of gap junction activity after oxidative stress. Binds and phosphorylates GRIA4/GLUR4 glutamate receptor and regulates its function by increasing plasma membrane-associated GRIA4 expression. In primary cerebellar neurons treated with the agonist 3,5-dihyidroxyphenylglycine, functions downstream of the metabotropic glutamate receptor GRM5/MGLUR5 and phosphorylates GRIN1/NMDAR1 receptor which plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. May be involved in the regulation of hippocampal long-term potentiation (LTP), but ma
Subcellular Location Cytoplasm {ECO:0000250|UniProtKB:P63318}. Cytoplasm, perinuclear region. Cell membrane {ECO:0000269|PubMed:12471040, ECO:0000269|PubMed:14688616}; Peripheral membrane protein. Cell junction, synapse, synaptosome {ECO:0000269|PubMed:14688616}. Cell projection, dendrite {ECO:0000269|PubMed:10336135}. Note=Translocates to synaptic membranes on stimulation. {ECO:0000269|PubMed:14688616}.
Top Pathways Inflammatory mediator regulation of TRP channels, Oxytocin signaling pathway, Thyroid hormone synthesis, Retrograde endocannabinoid signaling, MicroRNAs in cancer

Rat Protein Kinase C Gamma Protein - abx068753 from Abbexa

Category Protein
Source E.coli
Species Rat

Protein Kinase C Gamma (PKCg), Rat - 20-6659 from ARP American Research Products

Category Protein
Prices $489.00
Sizes 50 µg
Source E.coli
Species Rat

Recombinant Protein Kinase C Gamma (PKCg) - RPA419Ra01 from Cloud-clone

Category Protein
Source E.coli
Species Rat

Recombinant Rat Protein kinase C gamma type(Prkcg) - CSB-YP018705RA CSB-EP018705RA CSB-BP018705RA CSB-MP018705RA from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Rat

PKC gamma, Recombinant Protein - MBS5304336 from MyBioSource

Category Protein
Prices $550.00
Sizes 5 µg
Source Sf-9 insect cells

Recombinant Rat PRKCG Protein - PRKCG-4680R from Creative Biomart

Category Protein
Source Mammalian Cells
Species Rat

PRKCG Recombinant Protein (OPCD06215) - OPCD06215 from Aviva Systems Biology

Category Protein
Source E.coli
Species Rat

Protein Kinase C Gamma (PKCg), Recombinant Protein - MBS2012152 from MyBioSource

Category Protein
Prices $185.00, $380.00, $585.00
Sizes 10 µg, 50 µg, 100 µg
Source Prokaryotic expression
Species Rat

Protein kinase C gamma type (Prkcg), Recombinant Protein - MBS1006825 from MyBioSource

Category Protein
Prices $1,500.00, $1,500.00, $1,730.00, $1,730.00, $2,570.00, $2,570.00, $3,010.00, $3,010.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Rat
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