INCENP

Gene Symbol	INCENP
Entrez Gene	3619
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	inner centromere protein antigens 135/155kDa
Other Description	binds and activates aurora-B and -C in vivo and in vitro|chromosomal passenger protein|inner centromere protein|inner centromere protein INCENP
Swissprots	A8MQD2 Q5Y192 Q9NQS7
Accessions	EAW74003 EAW74004 EAW74005 Q9NQS7 AF282265 AAF87584 AK056195 BAG51645 AK307633 AK310714 AW839685 AY714053 AAU04398 BC032678 BC098576 AAH98576 BC111732 CV569756 XM_006718533 XP_006718596 XM_011544995 XP_011543297 XM_011544996 XP_011543298 XM_011544997 XP_011543299 XM_011544998 XP_011543300 NM_001040694 NP_001035784 NM_020238 NP_064623
Function	Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Probably acts through association with AURKB or AURKC. Seems to bind directly to microtubules. Controls the kinetochore localization of BUB1. {ECO:0000269|PubMed:12925766, ECO:0000269|PubMed:15316025, ECO:0000269|PubMed:16760428}.
Subcellular Location	Chromosome, centromere. Cytoplasm, cytoskeleton, spindle. Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to inner kinetochore. Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis. Colocalizes with AURKB at mitotic chromosomes.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human INCENP peptide - ab39944 from Abcam Category Peptide

Human INCENP peptide - ab97425 from Abcam Category Peptide

Human INCENP protein fragment - ab135223 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

INCENP Blocking Peptide - abx062794 from Abbexa Category Peptide Species Human, Mouse, Rat

Recombinant Human INCENP, His-tagged - INCENP-7037H from Creative Biomart Category Protein Source Sf9 Cells Species Human

INCENP (aa826-919)-GST - 12-534 from EMD Millipore

INCENP protein-HIS Epitope - 009-001-S21 from Rockland Immunochemicals Inc Category Protein Prices $499.00 Sizes 50 µg Species Human

INCENP protein-HIS Epitope - 009-001-S21S from Rockland Immunochemicals Inc Category Protein Prices $265.00 Sizes 20 µg Species Human

INCENP Blocking Peptide - CBP1600 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

INCENP Peptide - BS60432P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Inner centromere protein(INCENP) ,partial - CSB-YP885694HU CSB-EP885694HU CSB-BP885694HU CSB-MP885694HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

INCENP antibody ( mAb ) , 200 ug - HM-AB1631 from Novatein Biosciences Prices $442.00 Sizes 200 µg

INCENP antibody ( mAb ) , 10 ug - HM-AB1632 from Novatein Biosciences Prices $91.00 Sizes 10 µg

INCENP Peptide, Human - M34GP07640H from Creative Peptides Category Peptide Source Synthetic. Species Human

INCENP Recombinant Protein Antigen - NBP2-57266PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

INCENP, Recombinant Protein - MBS515136 from MyBioSource Category Protein Prices $260.00, $415.00 Sizes 20 µg, 50 µg Source Sf9 insect cells using baculovirus Species Human

Inner centromere protein (INCENP), partial, Recombinant Protein - MBS1420648 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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