INCENP

Gene Symbol INCENP
Entrez Gene 3619
Alt Symbol -
Species Human
Gene Type protein-coding
Description inner centromere protein antigens 135/155kDa
Other Description binds and activates aurora-B and -C in vivo and in vitro|chromosomal passenger protein|inner centromere protein|inner centromere protein INCENP
Swissprots A8MQD2 Q5Y192 Q9NQS7
Accessions EAW74003 EAW74004 EAW74005 Q9NQS7 AF282265 AAF87584 AK056195 BAG51645 AK307633 AK310714 AW839685 AY714053 AAU04398 BC032678 BC098576 AAH98576 BC111732 CV569756 XM_006718533 XP_006718596 XM_011544995 XP_011543297 XM_011544996 XP_011543298 XM_011544997 XP_011543299 XM_011544998 XP_011543300 NM_001040694 NP_001035784 NM_020238 NP_064623
Function Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Probably acts through association with AURKB or AURKC. Seems to bind directly to microtubules. Controls the kinetochore localization of BUB1. {ECO:0000269|PubMed:12925766, ECO:0000269|PubMed:15316025, ECO:0000269|PubMed:16760428}.
Subcellular Location Chromosome, centromere. Cytoplasm, cytoskeleton, spindle. Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to inner kinetochore. Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis. Colocalizes with AURKB at mitotic chromosomes.

INCENP (A841) Antibody - 2786 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of Jurkat and MOLT4 cells using INCENP (A841) Antibody.

INCENP (P240) Antibody - 2807 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of Jurkat and MOLT4 cells using INCENP (P240) Antibody.

INCENP (B-4) - sc-376514 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
INCENP (B-4): sc-376514. Western blot analysis of INCENP expression in Jurkat whole cell lysate.

INCENP (C-18) - sc-47895 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

INCENP (C-14) - sc-47894 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
INCENP (C-14): sc-47894. Immunofluorescence staining of formalin-fixed HeLa cells showing cytoplasmic and nuclear localization. Kindly provided by Yang Xiang, Ph.D., Division of Newborn Medicine, Boston Childrens Hospital, Cell Biology Department, Harvard Medical School.

INCENP (K-20) - sc-47896 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
INCENP (K-20): sc-47896. Western blot analysis of INCENP expression in mouse prostate tissue extract.

INCENP (H-153) - sc-67175 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
INCENP (H-153): sc-67175. Western blot analysis of INCENP expression in Jurkat whole cell lysate.

INCENP (N-13) - sc-47897 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-INCENP antibody [58-217] - ab23956 from Abcam

Prices $391.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 58-217
ICC/IF image of ab23956 stained human HeLa cells. The cells were methanol fixed (5 min) and incubated with the antibody (ab23956, 1µg/ml) for 1h at room temperature. The secondary antibody (green) was Alexa Fluor® 488 goat anti-mouse IgG (H+L) used at a 1/1000 dilution for 1h. Image-iTTM FX Signal Enhancer was used as the primary blocking agent, 5% BSA (in TBS-T) was used for all other blocking steps. DAPI was used to stain the cell nuclei (blue). Alexa Fluor® 594 WGA was used to label plasma membranes (red).

Anti-INCENP antibody [58-217] - BSA and Azide free - ab175584 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 58-217

Anti-INCENP antibody [EPR3542(2)] - ab134112 from Abcam

Host Rabbit
Clonality Monoclonal
Clone EPR3542(2)
All lanes : Anti-INCENP antibody [EPR3542(2)] (ab134112) at 1/1000 dilutionLane 1 : Molt4 cell lysateLane 2 : Jurkat cell lysateLane 3 : PC3 cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP conjugated antibody at 1/2000 dilution

Anti-INCENP Antibody (Pro240) - LS-C68343 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-INCENP Antibody (Ala841) - LS-C68344 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-INCENP Antibody (aa325-400, HRP) - LS-C142772 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-INCENP Antibody (aa325-400, Biotin) - LS-C142769 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-INCENP Antibody (aa325-400, DY650) - LS-C142770 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-INCENP Antibody (aa325-400, DY488) - LS-C142771 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-INCENP Antibody (aa325-400, DY550) - LS-C142773 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-INCENP Antibody - LS-C314103 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-INCENP Antibody (aa834-918) - LS-C311680 from LifeSpan Bioscience

Prices $250.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-INCENP Antibody (Internal, clone EPR3542(2)) - LS-C137830 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3542(2)
Immunofluorescent staining of HeLa cells using anti-INCENP antibody.

Anti-INCENP Antibody (C-Terminus) - LS-C345602 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of INCENP Antibody with human Fetal Lung lysate.

Anti-INCENP Antibody (aa325-400) - LS-C286333 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human INCENP by Immunocytochemistry. Sample: NBF-fixed asynchronous HeLa cells. Antibody: Affinity purified rabbit anti-INCENP used at a dilution of 1:250. Detection: Goat anti-rabbit IgG (h&l)-FITC used at a dilution of 1:100.

Anti-INCENP Antibody (clone 3D2) - LS-C169102 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D2
IHC of paraffin-embedded cervical cancer tissues using INCENP mouse monoclonal antibody with DAB staining.

INCENP Antibody (3D2) - NBP2-37471 from Novus Biologicals

Prices $369.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3D2
Western Blot: INCENP Antibody (3D2) [NBP2-37471] - Western blot analysis using INCENP mAb against HEK293 (1) and INCENP (AA: 369-583)-hIgGFc transfected HEK293 (2) cell lysate.
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