Gene Symbol | FMO3 |
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Entrez Gene | 2328 |
Alt Symbol | FMOII, TMAU, dJ127D3.1 |
Species | Human |
Gene Type | protein-coding |
Description | flavin containing monooxygenase 3 |
Other Description | FMO 3|FMO II|FMO form 2|dimethylaniline monooxygenase [N-oxide-forming] 3|dimethylaniline oxidase 3|hepatic flavin-containing monooxygenase 3|hepatic flavin-containing monooxygenase-3|trimethylamine monooxygenase |
Swissprots | Q8N5N5 Q14854 P31513 B2R816 |
Accessions | AAC51932 AAW65372 EAW90886 EAW90887 EAW90888 P31513 AI478384 AK223166 BAD96886 AK296105 BAH12258 AK298406 BAH12779 AK310785 AK313197 BAG36013 BC032016 AAH32016 BM453951 DQ892429 ABM83355 DQ895643 ABM86569 M83772 AAA86284 Z47552 CAA87632 XM_005245044 XP_005245101 XM_011509345 XP_011507647 XM_011509346 XP_011507648 NM_001002294 NP_001002294 NM_006894 NP_008825 |
Function | Involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. It N-oxygenates primary aliphatic alkylamines as well as secondary and tertiary amines. Plays an important role in the metabolism of trimethylamine (TMA), via the production of TMA N-oxide (TMAO). Is also able to perform S-oxidation when acting on sulfide compounds. |
Subcellular Location | Microsome membrane. Endoplasmic reticulum membrane. |
Tissue Specificity | Liver. |
Top Pathways | Drug metabolism - cytochrome P450 |
Human FMO3 full length protein - ab152391 from Abcam
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FMO3 Antibody Blocking Peptide - LS-E16318 from LifeSpan Bioscience
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FMO3 Antibody Blocking Peptide - LS-E16319 from LifeSpan Bioscience
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FMO3 Antibody Blocking Peptide - LS-E8534 from LifeSpan Bioscience
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Recombinant Human FMO3 Protein - H00002328-P01 from Novus Biologicals
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FMO3-Antibody-N-term-Blocking-Peptide - BP6901a from Abgent, a WuXi AppTec company
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Fmo3 Blocking Peptide - 33R-4593 from Fitzgerald
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FMO3 Blocking Peptide - 33R-6042 from Fitzgerald
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FMO3 Blocking Peptide - 33R-2997 from Fitzgerald
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FMO3 - H00002328-P01 from Acris Antibodies
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FMO3 fusion protein - Ag11405 from Proteintech Group
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FMO3 fusion protein - ag11421 from Proteintech Group
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Recombinant Human FMO3, His-tagged - FMO3-12944H from Creative Biomart
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Recombinant Human Flavin Containing Monooxygenase 3 - FMO3-718H from Creative Biomart
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Recombinant Human Dimethylaniline monooxygenase [N-oxide-forming] 3(FMO3) - CSB-YP008749HU CSB-EP008749HU CSB-BP008749HU CSB-MP008749HU from Cusabio
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FMO3 (transcript variant 1) - TP306506 from Acris Antibodies
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FMO3 (transcript variant 2) - TP312376 from Acris Antibodies
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FMO3 Recombinant Protein Antigen - NBP1-86083PEP from Novus Biologicals
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Dimethylaniline monooxygenase [N-oxide-forming] 3 (FMO3), Recombinant Protein - MBS958701 from MyBioSource
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Recombinant Human FMO3 Protein, His-tagged - FMO3-12945H from Creative Biomart
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