Gene Symbol | MEF2D |
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Entrez Gene | 4209 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | myocyte enhancer factor 2D |
Other Description | MADS box transcription enhancer factor 2, polypeptide D|myocyte-specific enhancer factor 2D |
Swissprots | D3DVC0 Q5T9U6 Q5T9U5 Q14814 Q14815 |
Accessions | AAA59579 CBX47582 EAW52948 EAW52950 EAW52951 EAW52952 Q14814 AB210005 BAE06087 AF086193 AK027180 AK056972 AK308641 BC018985 BC032479 AAH32479 BC040949 AAH40949 BC054520 AAH54520 BX640792 BX647226 DC377787 L16794 AAA93194 R42560 XM_005245169 XP_005245226 XM_005245170 XP_005245227 XM_006711330 XP_006711393 XM_006711332 XP_006711395 XM_006711333 XP_006711396 XM_006711334 XP_006711397 XM_011509569 XP_011507871 XM_011509570 XP_011507872 NM_001271629 NP_001258558 NM_005920 NP_005911 |
Function | Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle- specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00251, ECO:0000269|PubMed:12691662, ECO:0000269|PubMed:15743823}. Note=Translocated by HDAC4 to nuclear dots. |
Top Pathways | cGMP-PKG signaling pathway |
Human MEF2D full length protein - ab152520 from Abcam
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Human MEF2D protein fragment - ab152521 from Abcam
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MEF2D Antibody Blocking Peptide - LS-E1171 from LifeSpan Bioscience
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MEF2D Antibody Blocking Peptide - LS-E3044 from LifeSpan Bioscience
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MEF2D Antibody Blocking Peptide - LS-E13933 from LifeSpan Bioscience
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Recombinant Human MEF2D Protein - H00004209-P01 from Novus Biologicals
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MEF2D-Antibody-N-term-Blocking-peptide - BP11710a from Abgent, a WuXi AppTec company
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MEF2D-Antibody-Center-Blocking-Peptide - BP14178c from Abgent, a WuXi AppTec company
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MEF2D Protein Lysate (APL10199) - APL10199 from Aviva Systems Biology
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MEF2D Protein Lysate (APL10200) - APL10200 from Aviva Systems Biology
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MEF2D - H00004209-P01-10 from Acris Antibodies
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MEF2D - H00004209-P01-25 from Acris Antibodies
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MEF2D - H00004209-Q01-10 from Acris Antibodies
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MEF2D - H00004209-Q01-25 from Acris Antibodies
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MEF2D fusion protein - Ag5700 from Proteintech Group
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MEF2D fusion protein - Ag14898 from Proteintech Group
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Recombinant Human MEF2D, His-tagged - MEF2D-817H from Creative Biomart
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p-MEF2D (S444) Peptide - BS4326P from Bioworld Technology
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Recombinant Human Myocyte-specific enhancer factor 2D(MEF2D) - CSB-YP613522HU CSB-EP613522HU CSB-BP613522HU CSB-MP613522HU from Cusabio
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MEF2D (pS444) Blocking Peptide - abx161673 from Abbexa
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MEF2D - TP308748 from Acris Antibodies
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MEF2D Recombinant Protein Antigen - NBP1-85795PEP from Novus Biologicals
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MEF2D Recombinant Protein Antigen - NBP1-85788PEP from Novus Biologicals
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MEF2D Protein Lysate - orb333179 from Biorbyt
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MEF2D Protein Lysate - orb333180 from Biorbyt
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