Gene Symbol | MEF2D |
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Entrez Gene | 4209 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | myocyte enhancer factor 2D |
Other Description | MADS box transcription enhancer factor 2, polypeptide D|myocyte-specific enhancer factor 2D |
Swissprots | D3DVC0 Q5T9U6 Q5T9U5 Q14814 Q14815 |
Accessions | AAA59579 CBX47582 EAW52948 EAW52950 EAW52951 EAW52952 Q14814 AB210005 BAE06087 AF086193 AK027180 AK056972 AK308641 BC018985 BC032479 AAH32479 BC040949 AAH40949 BC054520 AAH54520 BX640792 BX647226 DC377787 L16794 AAA93194 R42560 XM_005245169 XP_005245226 XM_005245170 XP_005245227 XM_006711330 XP_006711393 XM_006711332 XP_006711395 XM_006711333 XP_006711396 XM_006711334 XP_006711397 XM_011509569 XP_011507871 XM_011509570 XP_011507872 NM_001271629 NP_001258558 NM_005920 NP_005911 |
Function | Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle- specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00251, ECO:0000269|PubMed:12691662, ECO:0000269|PubMed:15743823}. Note=Translocated by HDAC4 to nuclear dots. |
Top Pathways | cGMP-PKG signaling pathway |
MEF-2D (H-11) - sc-271153 from Santa Cruz Biotechnology
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MEF-2D (C-17) - sc-13922 from Santa Cruz Biotechnology
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MEF-2D (H-57) - sc-366368 from Santa Cruz Biotechnology
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MEF-2D (P-17) - sc-13921 from Santa Cruz Biotechnology
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MEF-2D (9) - sc-136196 from Santa Cruz Biotechnology
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Anti-MEF2D (phospho S444) antibody - ab59200 from Abcam
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Anti-MEF2D antibody - ab32845 from Abcam
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Anti-MEF2D antibody - ab167521 from Abcam
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Anti-MEF2D antibody - ab60717 from Abcam
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Anti-MEF2D antibody - ab104515 from Abcam
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Anti-MEF2D antibody - ab93257 from Abcam
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Anti-MEF2D Antibody (aa108-136) - LS-C164130 from LifeSpan Bioscience
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Anti-MEF2D Antibody (aa251-279, AP) - LS-C262952 from LifeSpan Bioscience
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Anti-MEF2D Antibody (aa410-459) - LS-C199248 from LifeSpan Bioscience
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Anti-MEF2D Antibody (clone 4D6) - LS-C197668 from LifeSpan Bioscience
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Anti-MEF2D Antibody (aa251-279, APC) - LS-C262953 from LifeSpan Bioscience
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Anti-MEF2D Antibody (aa251-279, Biotin) - LS-C262954 from LifeSpan Bioscience
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Anti-MEF2D Antibody (aa108-136, AP) - LS-C262958 from LifeSpan Bioscience
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Anti-MEF2D Antibody (aa251-279, FITC) - LS-C262955 from LifeSpan Bioscience
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Anti-MEF2D Antibody (aa251-279, Azide-free, HRP) - LS-C262957 from LifeSpan Bioscience
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Anti-MEF2D Antibody (aa251-279, PE) - LS-C262959 from LifeSpan Bioscience
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Anti-MEF2D Antibody (aa108-136, Azide-free, HRP) - LS-C262963 from LifeSpan Bioscience
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Anti-MEF2D Antibody (aa108-136, Biotin) - LS-C262961 from LifeSpan Bioscience
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Anti-MEF2D Antibody (aa475-521) - LS-C290194 from LifeSpan Bioscience
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Anti-MEF2D Antibody (aa108-136, PE) - LS-C262964 from LifeSpan Bioscience
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